KEGG   DRUG: Sergliflozin etabonateHelp
Entry
D06641                      Drug                                   

Name
Sergliflozin etabonate (USAN)
Formula
C23H28O9
Exact mass
448.1733
Mol weight
448.463
Structure
Mol fileKCF fileDB search
Class
Antidiabetic agent
 DG01794  SGLT2 inhibitor
 DG02044  Hypoglycemics
  DG01794  SGLT2 inhibitor
Efficacy
Antidiabetic, SGLT-2 inhibitor
Comment
Treatment of type 2 diabetes
Target
SLC5A2 (SGLT2) [HSA:6524] [KO:K14382]
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC5
    SLC5A2 (SGLT2)
     D06641  Sergliflozin etabonate (USAN)
BRITE hierarchy
Other DBs
CAS: 408504-26-7
PubChem: 47208292
ChEMBL: CHEMBL450044
LigandBox: D06641
LinkDB All DBs
KCF data Show

ATOM        32
            1   C1y C    12.1800  -25.3400
            2   C1y C    12.1800  -26.7400
            3   C1y C    13.3924  -27.4400
            4   C1y C    14.6049  -26.7400
            5   O2x O    14.6049  -25.3400
            6   C1y C    13.3924  -24.6400
            7   O2a O    15.8360  -27.4510
            8   C8y C    15.8360  -28.8510
            9   C8x C    14.6165  -29.5552
            10  C8x C    14.6166  -30.9552
            11  C8x C    15.8291  -31.6551
            12  C8x C    17.0486  -30.9509
            13  C8y C    17.0485  -29.5509
            14  C1b C    18.2892  -28.8343
            15  C8y C    19.4897  -29.5273
            16  C8x C    19.4900  -30.9397
            17  C8x C    20.7027  -31.6394
            18  C8y C    21.9149  -30.9390
            19  C8x C    21.9145  -29.5267
            20  C8x C    20.7019  -28.8270
            21  O2a O    23.1243  -31.6368
            22  C1a C    24.3169  -30.9477
            23  O1a O    13.3924  -28.8398
            24  O1a O    10.9676  -27.4400
            25  O1a O    10.9676  -24.6400
            26  C1b C    13.3924  -23.2402
            27  O7a O    12.1632  -22.5303
            28  C7a C    12.1632  -21.1303
            29  O6a O    13.3839  -20.4254
            30  O7a O    10.9675  -20.4401
            31  C1b C     9.7721  -21.1305
            32  C1a C     8.5847  -20.4450
BOND        34
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     4   7 1 #Up
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11   10  11 2
            12   11  12 1
            13   12  13 2
            14    8  13 1
            15   13  14 1
            16   14  15 1
            17   15  16 2
            18   16  17 1
            19   17  18 2
            20   18  19 1
            21   19  20 2
            22   15  20 1
            23   18  21 1
            24   21  22 1
            25    3  23 1 #Down
            26    2  24 1 #Up
            27    1  25 1 #Down
            28    6  26 1 #Up
            29   26  27 1
            30   27  28 1
            31   28  29 2
            32   28  30 1
            33   30  31 1
            34   31  32 1

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