KEGG   DRUG: Tesamorelin
Entry
D06655                      Drug                                   
Name
Tesamorelin (USAN)
Formula
C221H366N72O67S
Exact mass
5132.7166
Mol weight
5135.78
Sequence
C6H9O-Tyr Ala Asp Ala Ile Phe Thr Asn Ser Tyr Arg Lys Leu Gly Gln
Leu Ser Ala Arg Lys Leu Leu Gln Asp Ile Met Ser Arg Gln Gln Gly
Glu Ser Asn Gln Glu Arg Gly Ala Arg Ala Arg Leu-NH2
  Type
Peptide
Remark
ATC code: H01AC06
Chemical structure group: DG00495
Product (DG00495): D09015<US>
Efficacy
Growth hormone releasing hormone receptor agonist
Comment
growth hormone-releasing hormone (GH-RH) [HSA:2691] [KO:K05260] analog
For reduction of visceral adipose tissue in patients receiving antiretroviral therapy
Target
GHRHR [HSA:2692] [KO:K04584]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H01 PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES
   H01A ANTERIOR PITUITARY LOBE HORMONES AND ANALOGUES
    H01AC Somatropin and somatropin agonists
     H01AC06 Tesamorelin
      D06655  Tesamorelin (USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Secretin receptor family
   Growth hormone-releasing hormone
    GHRHR
     D06655  Tesamorelin (USAN)
Other DBs
CAS: 218949-48-5
PubChem: 47208306
ChEBI: 63626
LinkDB

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