| Entry |
|
|---|
| Name |
Amtolmetin guacil (INN);
Artromed (TN) |
|---|
| Formula |
C24H24N2O5
|
|---|
| Exact mass |
420.1685
|
|---|
| Mol weight |
420.46
|
|---|
| Structure |
|
|---|
| Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
|
|---|
| Efficacy |
Analgesic, Anti-inflammatory, Antipyretic, COX inhibitor |
|---|
| Comment |
Nonsteroidal anti-inflammatory drug (NSAID)
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
D07453 Amtolmetin guacil
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D07453 Amtolmetin guacil (INN)
PTGS2 (COX2)
D07453 Amtolmetin guacil (INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 31
1 O7a O 31.0100 -20.4400
2 C7a C 29.8200 -19.7400
3 C1b C 28.5600 -20.4400
4 N1b N 27.3700 -19.7400
5 C5a C 26.1800 -20.4400
6 C1b C 24.9200 -19.7400
7 C8y C 23.7300 -20.4400
8 C8y C 32.2000 -19.7400
9 C8x C 32.2000 -18.3400
10 C8x C 33.4600 -17.6400
11 C8x C 34.6500 -18.3400
12 C8x C 34.6500 -19.7400
13 C8y C 33.4600 -20.4400
14 O2a O 33.4600 -21.8400
15 C1a C 34.6500 -22.5400
16 O6a O 29.8200 -18.3400
17 O5a O 26.1800 -21.8400
18 C8x C 23.3100 -21.7700
19 C8x C 21.9100 -21.7700
20 C8y C 21.4900 -20.4400
21 N4y N 22.6100 -19.6000
22 C1a C 22.6100 -18.2000
23 C5a C 20.3000 -19.7400
24 C8y C 19.1100 -20.4400
25 O5a O 20.3000 -18.3400
26 C8x C 19.1100 -21.8400
27 C8x C 17.8500 -22.5400
28 C8y C 16.7300 -21.8400
29 C8x C 16.7300 -20.4400
30 C8x C 17.8500 -19.7400
31 C1a C 15.4700 -22.5400
BOND 33
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 6 7 1
7 1 8 1
8 8 9 2
9 9 10 1
10 10 11 2
11 11 12 1
12 12 13 2
13 8 13 1
14 13 14 1
15 14 15 1
16 2 16 2
17 5 17 2
18 7 18 2
19 18 19 1
20 19 20 2
21 20 21 1
22 7 21 1
23 21 22 1
24 23 24 1
25 23 20 1
26 23 25 2
27 24 26 2
28 26 27 1
29 27 28 2
30 28 29 1
31 29 30 2
32 24 30 1
33 28 31 1
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|---|
