KEGG   DRUG: Allopurinol sodium
Entry
D07564                      Drug                                   

Name
Allopurinol sodium;
Aloprim (TN)
Product
  Generic
Formula
C5H3N4O. Na
Exact mass
158.0205
Mol weight
158.0933
Structure
Class
Cardiovascular agent
 DG01503  Xanthine dehydrogenase inhibitor
Metabolizing enzyme inhibitor
 DG01634  CYP1A2 inhibitor
Remark
ATC code: M04AA01
Chemical structure group: DG00779
Product (DG00779): D00224<JP/US> D07564<US>
Efficacy
Gout suppressant, Uric acid biosynthesis inhibitor, Xanthine oxidase inhibitor
Target
XDH [HSA:7498] [KO:K00106]
  Pathway
hsa00230  Purine metabolism
Interaction
CYP inhibition: CYP1A2 [HSA:1544]
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 M MUSCULO-SKELETAL SYSTEM
  M04 ANTIGOUT PREPARATIONS
   M04A ANTIGOUT PREPARATIONS
    M04AA Preparations inhibiting uric acid production
     M04AA01 Allopurinol
      D07564  Allopurinol sodium <US>
USP drug classification [BR:br08302]
 Antigout Agents
  Allopurinol
   D07564  Allopurinol sodium
 Antineoplastics
  Treatment Adjuncts
   Allopurinol
    D07564  Allopurinol sodium
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Xanthine dehydrogenase/oxidase
    XDH
     D07564  Allopurinol sodium <US>
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D07564
Other DBs
CAS: 17795-21-0
PubChem: 51091885
LigandBox: D07564
LinkDB
KCF data

ATOM        11
            1   C8y C    24.0800  -17.9200
            2   C8y C    24.0800  -19.3200
            3   C8y C    25.2700  -17.2200
            4   N4x N    22.7500  -17.5000
            5   N5x N    25.2700  -20.0200
            6   C8x C    22.7500  -19.7400
            7   N5x N    26.4600  -17.9200
            8   O1a O    25.2700  -15.8200 #-
            9   N5x N    21.9100  -18.6200
            10  C8x C    26.4600  -19.3200
            11  Z   Na   29.6800  -18.1300 #+
BOND        11
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 2
            7     3   8 1
            8     4   9 1
            9     5  10 2
            10    6   9 2
            11    7  10 1

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