| Entry |
|
|---|
| Name |
Clobetasol (INN);
Clobecort Amex (TN) |
|---|
| Formula |
C22H28ClFO4
|
|---|
| Exact mass |
410.1660
|
|---|
| Mol weight |
410.90
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Product (DG00422): | D01272<JP/US> |
|
|---|
| Efficacy |
Anti-inflammatory, Glucocorticoid receptor agonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AD Corticosteroids, very potent (group IV)
D07AD01 Clobetasol
D07715 Clobetasol (INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00422 Clobetasol
D07715 Clobetasol
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D07715 Clobetasol (INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00422 Clobetasol
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 28
1 C1z C 25.6900 -17.2200
2 C1z C 24.5000 -17.9200
3 C1y C 26.8800 -17.9200
4 O1a O 26.8800 -16.5900
5 C5a C 25.6900 -15.8900
6 C1y C 24.5000 -19.2500
7 C1x C 23.3800 -17.2200
8 C1a C 24.5000 -16.5900
9 C1x C 26.8800 -19.2500
10 C1b C 26.8800 -15.1900
11 O5a O 24.5000 -15.1900
12 C1y C 23.3800 -19.9500
13 C1y C 22.1900 -17.9200
14 X Cl 26.8800 -13.8600
15 C1z C 22.1900 -19.2500
16 C1x C 23.3800 -21.2800
17 O1a O 21.0000 -17.2200
18 C1z C 21.0000 -19.9500
19 X F 22.1900 -20.6500
20 C1x C 22.1900 -21.9800
21 C2y C 21.0000 -21.2800
22 C2x C 19.8100 -19.2500
23 C1a C 21.0000 -18.6200
24 C2x C 19.8100 -21.9800
25 C2x C 18.6900 -19.9500
26 C5x C 18.6900 -21.2800
27 O5x O 17.5000 -21.9800
28 C1a C 28.2100 -17.9200
BOND 31
1 1 5 1 #Up
2 2 6 1
3 2 7 1
4 2 8 1 #Up
5 3 9 1
6 5 10 1
7 5 11 2
8 6 12 1
9 7 13 1
10 10 14 1
11 12 15 1
12 12 16 1
13 13 17 1 #Up
14 15 18 1
15 15 19 1 #Down
16 16 20 1
17 18 21 1
18 18 22 1
19 18 23 1 #Up
20 21 24 2
21 22 25 2
22 24 26 1
23 26 27 2
24 6 9 1
25 13 15 1
26 20 21 1
27 25 26 1
28 3 28 1 #Up
29 1 2 1
30 1 3 1
31 1 4 1 #Down
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