| Entry |
|
|---|
| Name |
Cortisone (INN);
Cortisone (TN) |
|---|
| Formula |
C21H28O5
|
|---|
| Exact mass |
360.1937
|
|---|
| Mol weight |
360.44
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Product (DG00509): | D00973<JP/US> |
|
|---|
| Efficacy |
Anti-inflammatory, Glucocorticoid receptor agonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07225 | Glucocorticoid and mineralocorticoid receptor agonists/antagonists |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02AB Glucocorticoids
H02AB10 Cortisone
D07749 Cortisone (INN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA03 Cortisone
D07749 Cortisone (INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00509 Cortisone
D07749 Cortisone
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D07749 Cortisone (INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00509 Cortisone
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 26
1 C1x C 20.0900 -19.4600
2 C5x C 20.0900 -20.7900
3 C2x C 21.2800 -21.4900
4 C2y C 22.4000 -20.7900
5 C1z C 22.4000 -19.4600
6 C1x C 21.2800 -18.7600
7 C1x C 23.5900 -21.4900
8 C1x C 24.7800 -20.7900
9 C1y C 24.7800 -19.4600
10 C1y C 23.5900 -18.7600
11 C1y C 25.9700 -18.7600
12 C1z C 25.9700 -17.4300
13 C1x C 24.7800 -16.7300
14 C5x C 23.5900 -17.4300
15 C1x C 28.2800 -18.7600
16 C1x C 28.2800 -17.4300
17 C1z C 27.1600 -16.7300
18 C1a C 22.4000 -18.0600
19 C1a C 25.9700 -16.0300
20 C5a C 27.1600 -15.0500
21 O5x O 18.9000 -21.4900
22 O5x O 22.4000 -16.7300
23 C1b C 28.3500 -14.3500
24 O5a O 25.9700 -14.3500
25 O1a O 28.2800 -16.0300
26 O1a O 29.4700 -14.9800
BOND 29
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 11 15 1
18 15 16 1
19 16 17 1
20 12 17 1
21 5 18 1 #Up
22 12 19 1 #Up
23 17 20 1 #Up
24 2 21 2
25 14 22 2
26 20 23 1
27 20 24 2
28 17 25 1 #Down
29 23 26 1
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