| Entry |
|
|---|
| Name |
Dopamine (INN);
Medopa (TN) |
|---|
| Formula |
C8H11NO2
|
|---|
| Exact mass |
153.0790
|
|---|
| Mol weight |
153.18
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01703 Cardiotonic
DG01699 Catecholamine cardiotonic
Neuropsychiatric agent
DG01472 Dopamine agonist
Metabolizing enzyme substrate
DG01592 COMT substrate
DG02917 MAO substrate
DG03179 MAOB substrate
Transporter substrate
DG02854 SLC22A2 substrate
|
|---|
| Remark |
| Product (DG00213): | D00633<JP/US> |
|
|---|
| Efficacy |
Cardiotonic, Dopamine receptor agonist |
|---|
| Comment |
Catecholamine derivative
Precursor of Norepinephrine
Neurotransmitter
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Metabolism |
Enzyme: MAOB [HSA: 4129], COMT [HSA: 1312]
Transporter: SLC22A2 [HSA: 6582]
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07213 | Dopamine receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C01 CARDIAC THERAPY
C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
C01CA Adrenergic and dopaminergic agents
C01CA04 Dopamine
D07870 Dopamine (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01699 Catecholamine cardiotonic
DG00213 Dopamine
D07870 Dopamine
Neuropsychiatric agent
DG01472 Dopamine agonist
DG00213 Dopamine
D07870 Dopamine
Metabolizing enzyme substrate
DG01592 COMT substrate
DG00213 Dopamine
D07870 Dopamine
DG02917 MAO substrate
DG03179 MAOB substrate
DG00213 Dopamine
D07870 Dopamine
Transporter substrate
DG02854 SLC22A2 substrate
DG00213 Dopamine
D07870 Dopamine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD
D07870 Dopamine (INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D07870
Drug transporters
D07870
Prodrugs [br08324.html]
D07870
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01699 Catecholamine cardiotonic
DG00213 Dopamine
Neuropsychiatric agent
DG01472 Dopamine agonist
DG00213 Dopamine
Metabolizing enzyme substrate
DG01592 COMT substrate
DG00213 Dopamine
DG02917 MAO substrate
DG03179 MAOB substrate
DG00213 Dopamine
Transporter substrate
DG02854 SLC22A2 substrate
DG00213 Dopamine
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 11
1 C8y C 27.5800 -20.4400
2 C8x C 26.3200 -19.7400
3 C8x C 27.5800 -21.9100
4 C1b C 28.8400 -19.7400
5 C8y C 25.1300 -20.4400
6 C8x C 26.3200 -22.6100
7 C1b C 30.0300 -20.4400
8 C8y C 25.1300 -21.9100
9 O1a O 23.9400 -19.7400
10 N1a N 31.2200 -19.7400
11 O1a O 23.9400 -22.5400
BOND 11
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 2
5 3 6 1
6 4 7 1
7 5 8 1
8 5 9 1
9 7 10 1
10 8 11 1
11 6 8 2
|
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