| Entry |
|
|---|
| Name |
Hydromorphone (INN) |
|---|
| Formula |
C17H19NO3
|
|---|
| Exact mass |
285.1365
|
|---|
| Mol weight |
285.34
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
Analgesic
DG01984 Opioid analgesics
Metabolizing enzyme substrate
DG02924 UGT substrate
|
|---|
| Remark |
| Product (DG00811): | D00839<JP/US> |
|
|---|
| Efficacy |
Analgesic (narcotic), Opioid receptor agonist |
|---|
| Comment |
Opium alkaloid
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Metabolism |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07224 | Opioid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N02 ANALGESICS
N02A OPIOIDS
N02AA Natural opium alkaloids
N02AA03 Hydromorphone
D08047 Hydromorphone (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG00811 Hydromorphone
D08047 Hydromorphone
Analgesic
DG01984 Opioid analgesics
DG00811 Hydromorphone
D08047 Hydromorphone
Metabolizing enzyme substrate
DG02924 UGT substrate
DG00811 Hydromorphone
D08047 Hydromorphone
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D08047 Hydromorphone (INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D08047
Narcotics and psychotropics in Japan [br08308.html]
Narcotics by Control Act Article 2 Table 1 (74 substances)
D08047
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG00811 Hydromorphone
Analgesic
DG01984 Opioid analgesics
DG00811 Hydromorphone
Metabolizing enzyme substrate
DG02924 UGT substrate
DG00811 Hydromorphone
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 21
1 C1z C 23.0300 -18.6200
2 C8y C 23.0300 -17.2900
3 C1y C 24.2200 -19.2500
4 C1y C 21.9100 -19.1800
5 C1x C 24.2200 -17.9900
6 C8y C 21.9100 -16.6600
7 C8y C 24.2200 -16.6600
8 C1y C 25.3400 -18.6200
9 C1x C 24.2200 -20.5100
10 O2x O 20.5800 -17.9200
11 C5x C 21.9100 -20.5100
12 C1x C 26.3900 -17.9900
13 C8y C 21.9100 -15.3300
14 C1x C 25.3400 -17.3600
15 C8x C 24.2200 -15.3300
16 N1y N 26.3900 -19.2500
17 C1x C 23.0300 -21.2100
18 O5x O 20.7900 -21.2100
19 C8x C 23.1000 -14.7000
20 O1a O 20.7900 -14.7000
21 C1a C 27.7900 -19.2500
BOND 25
1 1 2 1
2 1 3 1
3 1 4 1
4 1 5 1 #Up
5 2 6 2
6 2 7 1
7 3 8 1
8 3 9 1
9 4 10 1 #Down
10 4 11 1
11 5 12 1
12 6 13 1
13 7 14 1
14 7 15 2
15 8 16 1 #Up
16 9 17 1
17 11 18 2
18 13 19 2
19 13 20 1
20 6 10 1
21 8 14 1
22 11 17 1
23 12 16 1
24 15 19 1
25 16 21 1
|
|---|
