| Entry |
|
|---|
| Name |
Isoxsuprine (INN);
Dilator (TN) |
|---|
| Formula |
C18H23NO3
|
|---|
| Exact mass |
301.1678
|
|---|
| Mol weight |
301.38
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
|
|---|
| Remark |
| Product (DG00277): | D01748<JP> |
|
|---|
| Efficacy |
Vasodilator (peripheral), beta2-Adrenergic receptor agonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C04 PERIPHERAL VASODILATORS
C04A PERIPHERAL VASODILATORS
C04AA 2-amino-1-phenylethanol derivatives
C04AA01 Isoxsuprine
D08092 Isoxsuprine (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
DG00277 Isoxsuprine
D08092 Isoxsuprine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB2
D08092 Isoxsuprine (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
DG00277 Isoxsuprine
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 22
1 C8y C 20.5100 -17.5700
2 C1c C 21.7700 -18.2700
3 C1c C 22.9600 -17.5700
4 N1b N 24.1500 -18.2700
5 C1c C 25.4100 -17.5700
6 C1b C 26.6000 -18.2700
7 O2a O 27.7900 -17.5700
8 C1a C 22.9600 -16.1700
9 C1a C 25.4100 -16.1700
10 C8y C 29.0500 -18.2700
11 C8x C 29.0500 -19.6700
12 C8x C 30.2400 -20.3700
13 C8x C 31.4300 -19.6700
14 C8x C 31.4300 -18.2700
15 C8x C 30.2400 -17.5700
16 O1a O 21.7700 -19.6700
17 C8x C 20.5100 -16.2400
18 C8x C 19.3200 -15.5400
19 C8y C 18.1300 -16.2400
20 C8x C 18.1300 -17.6400
21 C8x C 19.3200 -18.3400
22 O1a O 16.8700 -15.5400
BOND 23
1 5 6 1
2 2 3 1
3 6 7 1
4 10 11 2
5 11 12 1
6 12 13 2
7 13 14 1
8 14 15 2
9 15 10 1
10 2 16 1
11 3 8 1
12 3 4 1
13 5 9 1
14 1 2 1
15 7 10 1
16 1 17 2
17 17 18 1
18 18 19 2
19 19 20 1
20 20 21 2
21 21 1 1
22 4 5 1
23 19 22 1
|
|---|
