| Entry |
|
|---|
| Name |
Lisinopril (INN);
Zestril (TN) |
|---|
| Formula |
C21H31N3O5
|
|---|
| Exact mass |
405.2264
|
|---|
| Mol weight |
405.49
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
|
|---|
| Remark |
| Product (DG00336): | D00362<JP/US> |
| Product (mixture): | D10268<US> |
|
|---|
| Efficacy |
Antihypertensive, Angiotensin-converting enzyme inhibitor |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07217 | Renin-angiotensin system inhibitors |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
C09A ACE INHIBITORS, PLAIN
C09AA ACE inhibitors, plain
C09AA03 Lisinopril
D08131 Lisinopril (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG00336 Lisinopril
D08131 Lisinopril
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
DG00336 Lisinopril
D08131 Lisinopril
Target-based classification of drugs [BR:br08310]
Peptidases and inhibitors
Metallo peptidases
Family M2
ACE (CD143)
D08131 Lisinopril (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG00336 Lisinopril
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
DG00336 Lisinopril
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 29
1 N1y N 28.4900 -18.5500
2 C1y C 29.6100 -19.3900
3 C5a C 27.3000 -19.2500
4 C1x C 28.9100 -17.2200
5 C1x C 30.7300 -18.5500
6 C6a C 29.6100 -20.7900
7 C1c C 26.0400 -18.5500
8 O5a O 27.3000 -20.6500
9 C1x C 30.3100 -17.2200
10 O6a O 30.8000 -21.4900
11 O6a O 28.3500 -21.4900
12 N1b N 24.8500 -19.2500
13 C1b C 26.0400 -17.1500
14 C1c C 23.6600 -18.5500
15 C1b C 27.3000 -16.4500
16 C1b C 22.4000 -19.2500
17 C6a C 23.6600 -17.1500
18 C1b C 27.3000 -15.0500
19 C1b C 21.2100 -18.5500
20 O6a O 24.8500 -16.4500
21 O6a O 22.4000 -16.4500
22 C1b C 26.0400 -14.3500
23 C8y C 20.0200 -19.2500
24 N1a N 24.8500 -15.0500
25 C8x C 20.0200 -20.6500
26 C8x C 18.7600 -18.5500
27 C8x C 18.7600 -21.3500
28 C8x C 17.5700 -19.2500
29 C8x C 17.5700 -20.6500
BOND 30
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1 #Up
6 3 7 1
7 3 8 2
8 4 9 1
9 6 10 1
10 6 11 2
11 7 12 1
12 7 13 1 #Up
13 12 14 1
14 13 15 1
15 14 16 1
16 14 17 1 #Up
17 15 18 1
18 16 19 1
19 17 20 1
20 17 21 2
21 18 22 1
22 19 23 1
23 22 24 1
24 23 25 1
25 23 26 2
26 25 27 2
27 26 28 1
28 27 29 1
29 5 9 1
30 28 29 2
|
|---|
