KEGG   DRUG: Oxprenolol
Entry
D08318                      Drug                                   

Name
Oxprenolol (INN);
Oxprenolol (TN)
Formula
C15H23NO3
Exact mass
265.1678
Mol weight
265.348
Structure
Simcomp
Class
Cardiovascular agent
 DG01653  Antiarrhythmics
  DG01806  Class II antiarrhythmic agent
 DG01466  Adrenergic receptor antagonist
  DG01464  beta-Adrenergic receptor antagonist
   DG01461  beta1-Adrenergic receptor antagonist
   DG01462  beta2-Adrenergic receptor antagonist
   DG01463  beta3-Adrenergic receptor antagonist
Remark
ATC code: C07AA02
Chemical structure group: DG00304
Efficacy
Antiarrhythmic, Vasodilator, beta-Adrenergic receptor antagonist
Comment
Propranolol derivative
Target
ADRB [HSA:153 154 155] [KO:K04141 K04142 K04143]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AA Beta blocking agents, non-selective
     C07AA02 Oxprenolol
      D08318  Oxprenolol (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    ADRB
     D08318  Oxprenolol (INN)
Other DBs
CAS: 6452-71-7
PubChem: 96025005
ChEMBL: CHEMBL546
DrugBank: DB01580
LigandBox: D08318
NIKKAJI: J8.410G
LinkDB
KCF data

ATOM        19
            1   O2a O    20.3700  -15.6800
            2   C1b C    21.5600  -14.9800
            3   C1c C    22.8200  -15.6800
            4   C1b C    24.0100  -14.9800
            5   N1b N    25.2000  -15.6800
            6   C1c C    26.4600  -14.9800
            7   C1a C    27.6500  -15.6800
            8   O1a O    22.8200  -17.0800
            9   C1a C    26.4600  -13.5800
            10  C8y C    20.3700  -17.0800
            11  C8y C    19.1100  -17.7800
            12  C8x C    19.1100  -19.1800
            13  C8x C    20.3700  -19.8800
            14  C8x C    21.5600  -19.1800
            15  C8x C    21.5600  -17.7800
            16  O2a O    17.9200  -17.0800
            17  C1b C    16.7300  -17.7800
            18  C2b C    15.5400  -17.0800
            19  C2a C    14.3500  -17.7800
BOND        19
            1     3   4 1
            2     4   5 1
            3     5   6 1
            4     6   7 1
            5     3   8 1
            6     6   9 1
            7     1   2 1
            8     2   3 1
            9     1  10 1
            10   10  11 2
            11   11  12 1
            12   12  13 2
            13   13  14 1
            14   14  15 2
            15   10  15 1
            16   11  16 1
            17   16  17 1
            18   17  18 1
            19   18  19 2

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