KEGG   DRUG: Quinagolide hydrochloride
Entry
D08457                      Drug                                   

Name
Quinagolide hydrochloride (BAN);
Norprolac (TN)
Formula
C20H33N3O3S. HCl
Exact mass
431.2009
Mol weight
432.0203
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01472  Dopamine agonist
  DG01468  Dopamine D2-receptor agonist
 DG01964  Ergot alkaloid
Remark
ATC code: G02CB04
Chemical structure group: DG00454
Efficacy
Antihyperprolactinemia, Dopamine D2 receptor agonist
Comment
Prolactin inhibitor
Target
DRD2 [HSA:1813] [KO:K04145]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04728  Dopaminergic synapse
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G02 OTHER GYNECOLOGICALS
   G02C OTHER GYNECOLOGICALS
    G02CB Prolactine inhibitors
     G02CB04 Quinagolide
      D08457  Quinagolide hydrochloride (BAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD2
     D08457  Quinagolide hydrochloride (BAN)
Other DBs
CAS: 94424-50-7
PubChem: 96025143
LigandBox: D08457
LinkDB
KCF data

ATOM        28
            1   C8x C    18.2000  -17.5700
            2   C8x C    18.2000  -18.9700
            3   C8x C    19.4600  -19.6700
            4   C8y C    20.6500  -18.9700
            5   C8y C    20.6500  -17.5700
            6   C8y C    19.4600  -16.8700
            7   C1x C    21.8400  -19.6700
            8   C1y C    23.1000  -18.9700
            9   C1y C    23.1000  -17.5700
            10  C1x C    21.8400  -16.8700
            11  N1y N    24.2900  -19.6700
            12  C1x C    25.4800  -18.9700
            13  C1y C    25.4800  -17.5700
            14  C1x C    24.2900  -16.8700
            15  O1a O    19.4600  -15.5400
            16  C1b C    24.2900  -21.0700
            17  C1b C    25.4800  -21.8400
            18  C1a C    26.7400  -21.1400
            19  N1b N    26.6700  -16.8700
            20  S4a S    26.6700  -15.5400
            21  N1c N    28.0700  -15.4700
            22  C1b C    28.7700  -16.7300
            23  C1b C    28.7700  -14.2800
            24  C1a C    30.1700  -14.2800
            25  C1a C    30.1700  -16.7300
            26  O3c O    26.6700  -14.0000
            27  O3c O    25.2700  -15.4700
            28  X   Cl   32.4100  -19.8800
BOND        29
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    8  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16    9  14 1
            17    6  15 1
            18   11  16 1
            19   16  17 1
            20   17  18 1
            21   19  20 1
            22   20  21 1
            23   21  22 1
            24   21  23 1
            25   23  24 1
            26   22  25 1
            27   20  26 2
            28   20  27 2
            29   13  19 1 #Down

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