KEGG   DRUG: Amlodipine besilate and atorvastatin calcium
Entry
D08488            Mixture   Drug                                   

Name
Amlodipine besilate and atorvastatin calcium;
Caduet (TN)
Product
  Generic
Component
Amlodipine besilate [DR:D00615], (Atorvastatin calcium hydrate [DR:D02258] | Atorvastatin calcium [DR:D00887] | Atorvastatin calcium propylene glycol solvate [DR:D11095])
Class
Cardiovascular agent
 DG01946  Hypolipidemic agent
Metabolizing enzyme substrate
 DG02913  CYP3A4 substrate
Remark
Therapeutic category: 2190
ATC code: C10BX03
Product: D08488<JP/US>
Efficacy
Antihyperlipidemic, Antihypertensive
  Disease
Hypertension [DS:H01633]
Coronary artery disease [DS:H01742]
Chronic stable angina [DS:H01632]
Hyperlipidemia [DS:H01635]
Metabolism
Enzyme: CYP3A4 [HSA:1576]
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C10 LIPID MODIFYING AGENTS
   C10B LIPID MODIFYING AGENTS, COMBINATIONS
    C10BX HMG CoA reductase inhibitors, other combinations
     C10BX03 Atorvastatin and amlodipine
      D08488  Amlodipine besilate and atorvastatin calcium <JP/US>
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Cardiovascular Combinations
   Amlodipine Besylate/ Atorvastatin Calcium
    D08488  Amlodipine besilate and atorvastatin calcium
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   219  Miscellaneous
    2190  Miscellaneous
     D08488  Amlodipine besilate and atorvastatin calcium
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D08488
Other DBs
PubChem: 96025174
LinkDB

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