KEGG   DRUG: Spiramycin adipateHelp
Entry
D08527                      Drug                                   

Name
Spiramycin adipate;
Rovamycina (TN);
Spiramaicina (TN)
Formula
C43H75N2O14R. C6H8O4
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antibacterial
 DG01551  Macrolide antibiotic
  DG01876  16-Membered ring macrolide antibiotic
Remark
ATC code: J01FA02
Chemical structure group: DG00602
Product (DG00602): D05908<JP> D02420<JP>
Efficacy
Antibiotic, Protein biosynthesis inhibitor
Target
50S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Drug interaction
Structure map
map07020  Macrolides and ketolides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
    J01FA Macrolides
     J01FA02 Spiramycin
      D08527  Spiramycin adipate
BRITE hierarchy
Other DBs
CAS: 68880-55-7
PubChem: 96025212
LinkDB All DBs
KCF data Show

ATOM        70
            1   C1y C    18.6900  -28.9100
            2   C1y C    19.7400  -29.6100
            3   O2a O    17.5700  -29.6100
            4   C1y C    18.6900  -27.6500
            5   C1y C    20.9300  -28.9100
            6   N1c N    19.7400  -30.8700 #+
            7   C1y C    16.4500  -30.2400
            8   O2x O    19.7400  -27.0200
            9   C1a C    17.5700  -27.0200
            10  C1y C    20.9300  -27.6500
            11  O1a O    22.0500  -29.6100
            12  C1a C    21.0000  -32.2000
            13  C1a C    18.7600  -32.2000
            14  C1x C    16.4500  -31.5000
            15  O2x O    15.3300  -29.6100
            16  O2a O    23.1700  -25.0600
            17  C1z C    15.3300  -32.2000
            18  C1y C    14.2100  -30.2400
            19  C1y C    19.7400  -21.3500
            20  C1y C    14.2100  -31.5000
            21  C1a C    14.4200  -33.3900
            22  O1a O    16.2400  -33.5300
            23  C1a C    13.0900  -29.6100
            24  C1y C    19.7400  -20.0200
            25  C1y C    18.6200  -22.0500
            26  O1a O    13.0900  -32.2000
            27  C1x C    18.5500  -19.3900
            28  C1b C    20.7900  -19.3900
            29  C1y C    18.6200  -23.3800
            30  O2a O    17.5700  -21.4200
            31  C1y C    18.5500  -18.0600
            32  C4a C    21.9100  -20.0200
            33  C1x C    17.4300  -24.0100
            34  C1y C    17.4300  -17.4300
            35  C1a C    19.6700  -17.4300
            36  O4a O    23.0300  -19.3900
            37  C7x C    16.2400  -23.3800
            38  C2x C    16.3100  -18.0600
            39  O2a O    17.4300  -16.1700
            40  O7x O    15.1200  -24.0100
            41  O6a O    16.2400  -22.0500
            42  C2x C    16.3100  -19.3900
            43  C1y C    13.9300  -23.3100
            44  C2x C    15.1900  -20.0200
            45  C1x C    13.9300  -21.9100
            46  C1a C    12.8800  -23.9400
            47  C2x C    15.1900  -21.3500
            48  C1a C    17.5700  -20.1600
            49  O2a O    19.7400  -24.0800
            50  R   R    19.7400  -25.2700
            51  C1y C    16.3100  -15.5400
            52  O2x O    16.3100  -14.2100
            53  C1y C    15.1900  -13.5800
            54  C1y C    14.0700  -14.2100
            55  C1x C    14.0700  -15.5400
            56  C1x C    15.1900  -16.1700
            57  C1a C    15.1900  -12.3200
            58  N1c N    12.8800  -13.2300 #+
            59  C1a C    12.8800  -11.6200
            60  C1a C    11.6900  -14.2800
            61  O6a O    27.4624  -23.1700 #-
            62  C6a C    28.6749  -23.8700
            63  C1b C    29.8873  -23.1700
            64  C1b C    31.0997  -23.8700
            65  C1b C    32.3122  -23.1700
            66  C1b C    33.5246  -23.8700
            67  C6a C    34.7370  -23.1700
            68  O6a O    35.9495  -23.8700 #-
            69  O6a O    28.6749  -25.2698
            70  O6a O    34.7370  -21.7701
BOND        72
            1    19  25 1
            2    20  26 1 #Up
            3    24  27 1
            4    24  28 1 #Down
            5    25  29 1
            6    25  30 1 #Down
            7    27  31 1
            8    28  32 1
            9    29  33 1
            10   31  34 1
            11   31  35 1 #Down
            12   32  36 2
            13   33  37 1
            14   34  38 1
            15   34  39 1 #Down
            16   37  40 1
            17   37  41 2
            18   38  42 2
            19   40  43 1
            20   42  44 1
            21   43  45 1
            22   43  46 1 #Down
            23   44  47 2
            24    8  10 1
            25   18  20 1
            26   45  47 1
            27   30  48 1
            28    1   2 1
            29    1   3 1 #Down
            30    1   4 1
            31    2   5 1
            32    2   6 1 #Up
            33    7   3 1 #Up
            34    4   8 1
            35    4   9 1 #Up
            36    5  10 1
            37    5  11 1 #Down
            38    6  12 1
            39   29  49 1 #Down
            40    6  13 1
            41   49  50 1
            42    7  14 1
            43    7  15 1
            44   51  39 1 #Up
            45   10  16 1 #Up
            46   14  17 1
            47   15  18 1
            48   19  16 1 #Down
            49   17  20 1
            50   51  52 1
            51   52  53 1
            52   53  54 1
            53   54  55 1
            54   55  56 1
            55   56  51 1
            56   17  21 1 #Down
            57   53  57 1 #Up
            58   17  22 1 #Up
            59   54  58 1 #Down
            60   18  23 1 #Down
            61   58  59 1
            62   19  24 1
            63   58  60 1
            64   61  62 1
            65   62  63 1
            66   63  64 1
            67   64  65 1
            68   65  66 1
            69   66  67 1
            70   67  68 1
            71   62  69 2
            72   67  70 2

» Japanese version   » Back

DBGET integrated database retrieval system