KEGG   DRUG: Talipexole
Entry
D08558                      Drug                                   

Name
Talipexole (INN)
Formula
C10H15N3S
Exact mass
209.0987
Mol weight
209.3112
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01472  Dopamine agonist
  DG01468  Dopamine D2-receptor agonist
 DG01967  Antiparkinson agent
Remark
Chemical structure group: DG01326
Product (DG01326): D01505<JP>
Efficacy
Antiparkinsonian, Dopamine D2 receptor agonist
Target
DRD2 [HSA:1813] [KO:K04145]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04728  Dopaminergic synapse
Interaction
Structure map
map07057  Antiparkinsonian agents
map07213  Dopamine receptor agonists/antagonists
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD2
     D08558  Talipexole (INN)
Other DBs
CAS: 101626-70-4
PubChem: 96025243
ChEMBL: CHEMBL279085
LigandBox: D08558
NIKKAJI: J33.385I
LinkDB
KCF data

ATOM        14
            1   C8y C    22.5400  -16.1000
            2   C8y C    22.5400  -17.5000
            3   N5x N    23.8700  -17.9200
            4   C8y C    24.7100  -16.8000
            5   S2x S    23.8700  -15.6800
            6   C1x C    21.4200  -15.1900
            7   C1x C    20.0900  -15.5400
            8   N1y N    19.4600  -16.8000
            9   C1x C    20.0900  -18.0600
            10  C1x C    21.4200  -18.3400
            11  C1b C    18.0600  -16.8000
            12  N1a N    26.1100  -16.8000
            13  C2b C    17.3600  -15.6100
            14  C2a C    15.9600  -15.6100
BOND        15
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     1   5 1
            6     7   8 1
            7     8   9 1
            8     6   7 1
            9     2  10 1
            10    1   6 1
            11    9  10 1
            12    8  11 1
            13    4  12 1
            14   11  13 1
            15   13  14 2

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