KEGG   DRUG: Estradiol and levonorgestrel
Entry
D09187            Mixture   Drug                                   

Name
Estradiol and levonorgestrel;
Wellnara (TN);
Climara pro (TN)
Product
Component
Estradiol [DR:D00105], Levonorgestrel [DR:D00950]
Class
Metabolizing enzyme substrate
 DG02913  CYP3A4 substrate
Remark
Therapeutic category: 2482
ATC code: G03FA11 G03FB09
Product: D09187<JP/US>
Efficacy
Osteoporosis agent, Replenisher (hormone)
  Disease
Osteoporosis [DS:H01593]
Comment
Treatment of Postmenopausal osteoporosis
Metabolism
Enzyme: CYP3A4 [HSA:1576]
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
   G03F PROGESTOGENS AND ESTROGENS IN COMBINATION
    G03FA Progestogens and estrogens, fixed combinations
     G03FA11 Levonorgestrel and estrogen
      D09187  Estradiol and levonorgestrel <JP/US>
    G03FB Progestogens and estrogens, sequential preparations
     G03FB09 Levonorgestrel and estrogen
      D09187  Estradiol and levonorgestrel <JP/US>
USP drug classification [BR:br08302]
 Hormonal Agents, Stimulant/Replacement/Modifying (Sex Hormones/Modifiers)
  Hormonal Agents, Stimulant/Replacement/Modifying (Sex Hormones/Modifiers), Other
   Estradiol/ Levonorgestrel
    D09187  Estradiol and levonorgestrel
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   248  Mixed hormone preparations
    2482  Estrogens and progestins
     D09187  Estradiol and levonorgestrel
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D09187
Other DBs
PubChem: 96025867
LinkDB

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