KEGG   DRUG: Dutogliptin tartrate
Entry
D09334                      Drug                                   

Name
Dutogliptin tartrate (USAN)
Formula
C10H20BN3O3. C4H6O6
Exact mass
391.1762
Mol weight
391.1819
Structure
Class
Antidiabetic agent
 DG01601  DPP-4 inhibitor
 DG02044  Hypoglycemics
  DG01601  DPP-4 inhibitor
Remark
Chemical structure group: DG01282
Efficacy
Antidiabetic, Dipeptidyl peptidase-4 (DPP-4) inhibitor
Comment
Treatment of type 2 diabetes
Target
DPP4 (CD26) [HSA:1803] [KO:K01278]
  Pathway
hsa04974  Protein digestion and absorption
Interaction
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases (EC3)
   Peptidyl-peptidases
    DPP4 (CD26)
     D09334  Dutogliptin tartrate (USAN)
Other DBs
CAS: 890402-81-0
PubChem: 96026014
LinkDB
KCF data

ATOM        27
            1   N1x N     9.7300  -23.6600
            2   C1x C    10.1500  -24.9200
            3   C1x C    11.5500  -24.9200
            4   C1y C    11.9700  -23.5900
            5   C1x C    10.8500  -22.7500
            6   N1b N    13.1600  -22.8900
            7   C1b C    14.3500  -23.5900
            8   C5a C    15.5400  -22.8900
            9   N1y N    16.7300  -23.5900
            10  O5a O    15.5400  -21.4200
            11  C1x C    17.0800  -24.9900
            12  C1x C    18.4800  -24.9900
            13  C1x C    18.9700  -23.7300
            14  C1y C    17.9200  -22.8200
            15  Z   B    17.9200  -21.4200
            16  O1a O    19.1800  -20.7200
            17  O1a O    16.7300  -20.6500
            18  C6a C    23.1700  -22.1200
            19  C1c C    24.3824  -22.8200
            20  O6a O    21.9576  -22.8200
            21  C1c C    25.5779  -22.1296
            22  C6a C    26.7653  -22.8151
            23  O6a O    23.1700  -20.7200
            24  O1a O    25.5780  -20.7203
            25  O6a O    27.9565  -22.1271
            26  O6a O    26.7655  -24.2198
            27  O1a O    24.3825  -24.2198
BOND        27
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     6   7 1
            7     4   6 1 #Down
            8     7   8 1
            9     8   9 1
            10    8  10 2
            11    9  11 1
            12   11  12 1
            13   12  13 1
            14   13  14 1
            15    9  14 1
            16   14  15 1 #Down
            17   15  16 1
            18   15  17 1
            19   18  19 1
            20   18  20 1
            21   19  21 1
            22   21  22 1
            23   18  23 2
            24   21  24 1 #Up
            25   22  25 1
            26   22  26 2
            27   19  27 1 #Up

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