KEGG   DRUG: Pozanicline tartrate
Entry
D09368                      Drug                                   

Name
Pozanicline tartrate (USAN)
Formula
C11H16N2O. C4H6O6
Exact mass
342.1427
Mol weight
342.3444
Structure
Class
Neuropsychiatric agent
 DG01571  Nicotinic cholinergic receptor partial agonist
Remark
Chemical structure group: DG01288
Efficacy
Dementia therapeutic agent, Nicotinic acetylcholine receptor partial agonist
Comment
Attention deficit/hyperactivity disorder (ADHD), dementia of the Alzheimer's type (AD)
Target
CHRNA4/CHRNB2 [HSA:1137 1141] [KO:K04806 K04813]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   Acetylcholine (nicotinic)
    CHRNA4/CHRNB2
     D09368  Pozanicline tartrate (USAN)
Other DBs
CAS: 945405-37-8
PubChem: 96026048
LigandBox: D09368
LinkDB
KCF data

ATOM        24
            1   C8y C    19.4197  -24.4214
            2   C8x C    19.4197  -25.8249
            3   C8x C    18.2268  -26.5266
            4   C8x C    16.9636  -25.8249
            5   N5x N    16.9636  -24.4214
            6   C8y C    18.2268  -23.7196
            7   O2a O    20.6127  -23.7196
            8   C1b C    21.8057  -24.4214
            9   C1y C    22.9986  -23.7196
            10  C1x C    23.4197  -22.3863
            11  C1x C    24.8232  -22.3863
            12  C1x C    25.2442  -23.7196
            13  N1x N    24.1214  -24.5617
            14  C1a C    18.2268  -22.3161
            15  C6a C    28.5425  -23.7196
            16  O6a O    27.3270  -24.4214
            17  C1c C    29.7726  -24.4298
            18  C1c C    30.9679  -23.7395
            19  C6a C    32.1553  -24.4250
            20  O6a O    33.3465  -23.7370
            21  O6a O    32.1555  -25.8298
            22  O6a O    28.5426  -22.3301
            23  O1a O    29.7727  -25.8298
            24  O1a O    30.9679  -22.3303
BOND        24
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     9   8 1 #Down
            10   10  11 1
            11   11  12 1
            12   12  13 1
            13   13   9 1
            14   10   9 1
            15    6  14 1
            16   15  16 1
            17   15  17 1
            18   17  18 1
            19   18  19 1
            20   19  20 1
            21   19  21 2
            22   15  22 2
            23   17  23 1 #Up
            24   18  24 1 #Up

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