KEGG   DRUG: Gosogliptin
Entry
D09625                      Drug                                   

Name
Gosogliptin (USAN/INN)
Formula
C17H24F2N6O
Exact mass
366.198
Mol weight
366.4089
Structure
Class
Antidiabetic agent
 DG01601  DPP-4 inhibitor
 DG02044  Hypoglycemics
  DG01601  DPP-4 inhibitor
Efficacy
Antidiabetic, Dipeptidyl peptidase-4 (DPP-4) inhibitor
Comment
Treatment of diabetes
Target
DPP4 (CD26) [HSA:1803] [KO:K01278]
  Pathway
hsa04974  Protein digestion and absorption
Interaction
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases (EC3)
   Peptidyl-peptidases
    DPP4 (CD26)
     D09625  Gosogliptin (USAN/INN)
Other DBs
CAS: 869490-23-3
PubChem: 124490365
ChEMBL: CHEMBL515387
PDB-CCD: PF2[PDBj]
LigandBox: D09625
LinkDB
KCF data

ATOM        26
            1   C8x C     9.7300  -25.8300
            2   C8x C     9.7300  -27.2300
            3   C8x C    10.9200  -27.9300
            4   N5x N    12.1800  -27.2300
            5   C8y C    12.1800  -25.8300
            6   N5x N    10.9200  -25.1300
            7   N1y N    13.3700  -25.1300
            8   C1x C    14.5600  -25.8300
            9   C1x C    15.8200  -25.1300
            10  N1y N    15.8200  -23.7300
            11  C1x C    14.6300  -23.0300
            12  C1x C    13.3700  -23.7300
            13  C1y C    17.0100  -23.0300
            14  N1x N    18.8300  -21.7000
            15  C1x C    17.4300  -21.7000
            16  C1x C    18.1300  -23.8700
            17  C1y C    19.2500  -23.0300
            18  C5a C    20.4400  -23.7300
            19  N1y N    21.6300  -23.0300
            20  O5a O    20.4400  -25.1300
            21  C1x C    23.4500  -21.7000
            22  C1x C    22.0500  -21.7000
            23  C1x C    22.7500  -23.8700
            24  C1z C    23.8700  -23.0300
            25  X   F    24.5700  -24.2900
            26  X   F    25.2700  -23.0300
BOND        29
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13    7  12 1
            14   13  10 1 #Down
            15   14  15 1
            16   15  13 1
            17   13  16 1
            18   16  17 1
            19   14  17 1
            20   17  18 1 #Down
            21   18  19 1
            22   18  20 2
            23   21  22 1
            24   22  19 1
            25   19  23 1
            26   23  24 1
            27   21  24 1
            28   24  25 1
            29   24  26 1

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