KEGG   DRUG: Amifampridine
Entry
D10228                      Drug                                   

Name
Amifampridine (USAN/INN);
Ruzurgi (TN)
Product
Formula
C5H7N3
Exact mass
109.064
Mol weight
109.1292
Structure
Simcomp
Remark
ATC code: N07XX05
Chemical structure group: DG02003
Product (DG02003): D10228<US> D10689<US>
Efficacy
Autoimmune disease treatment, Potassium channel blocker
  Disease
Lambert-Eaton myasthenic syndrome [DS:H01596]
Comment
Symptomatic treatment of Lambert-Eaton myasthenic syndrome (LEMS) in adults
Target
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N07 OTHER NERVOUS SYSTEM DRUGS
   N07X OTHER NERVOUS SYSTEM DRUGS
    N07XX Other nervous system drugs
     N07XX05 Amifampridine
      D10228  Amifampridine (USAN/INN) <US>
USP drug classification [BR:br08302]
 Central Nervous System Agents
  Central Nervous System, Other
   Amifampridine
    D10228  Amifampridine (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated ion channels
   Potassium channels
    KCNA
     D10228  Amifampridine (USAN/INN) <US>
    KCNB
     D10228  Amifampridine (USAN/INN) <US>
    KCNC
     D10228  Amifampridine (USAN/INN) <US>
    KCND
     D10228  Amifampridine (USAN/INN) <US>
Other DBs
CAS: 54-96-6
PubChem: 163312259
ChEMBL: CHEMBL354077
PDB-CCD: L89[PDBj]
LinkDB
KCF data

ATOM        8
            1   C8y C    11.0600  -18.8300
            2   C8x C    11.0600  -20.2300
            3   N5x N    12.2724  -20.9300
            4   C8x C    13.4849  -20.2300
            5   C8x C    13.4849  -18.8300
            6   C8y C    12.2724  -18.1300
            7   N1a N    12.2724  -16.7302
            8   N1a N     9.8476  -18.1300
BOND        8
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     6   7 1
            8     1   8 1

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