KEGG   DRUG: Susoctocog alfa
Entry
D10831                      Drug                                   

Name
Susoctocog alfa (INN);
Obizur (TN)
Sequence
AIRRYYLGAV ELSWDYRQSE LLRELHVDTR FPATAPGALP LGPSVLYKKT VFVEFTDQLF
SVARPRPPWM GLLGPTIQAE VYDTVVVTLK NMASHPVSLH AVGVSFWKSS EGAEYEDHTS
QREKEDDKVL PGKSQTYVWQ VLKENGPTAS DPPCLTYSYL SHVDLVKDLN SGLIGALLVC
REGSLTRERT QNLHEFVLLF AVFDEGKSWH SARNDSWTRA MDPAPARAQP AMHTVNGYVN
RSLPGLIGCH KKSVYWHVIG MGTSPEVHSI FLEGHTFLVR HHRQASLEIS PLTFLTAQTF
LMDLGQFLLF CHISSHHHGG MEAHVRVESC AEEPQLRRKA DEEEDYDDNL YDSDMDVVRL
DGDDVSPFIQ IRSVAKKHPK TWVHYISAEE EDWDYAPAVP SPSDRSYKSL YLNSGPQRIG
RKYKKARFVA YTDVTFKTRK AIPYESGILG PLLYGEVGDT LLIIFKNKAS RPYNIYPHGI
TDVSALHPGR LLKGWKHLKD MPILPGETFK YKWTVTVEDG PTKSDPRCLT RYYSSSINLE
KDLASGLIGP LLICYKESVD QRGNQMMSDK RNVILFSVFD ENQSWYLAEN IQRFLPNPDG
LQPQDPEFQA SNIMHSINGY VFDSLQLSVC LHEVAYWYIL SVGAQTDFLS VFFSGYTFKH
KMVYEDTLTL FPFSGETVFM SMENPGLWVL GCHNSDLRNR GMTALLKVYS CDRDIGDYYD
NTYEDIPGFL LSGKNVIEPR SFAQNSRPPS ASAPKPPVLR RHQRDISLPT FQPEEDKMDY
DDIFSTETKG EDFDIYGEDE NQDPRSFQKR TRHYFIAAVE QLWDYGMSES PRALRNRAQN
GEVPRFKKVV FREFADGSFT QPSYRGELNK HLGLLGPYIR AEVEDNIMVT FKNQASRPYS
FYSSLISYPD DQEQGAEPRH NFVQPNETRT YFWKVQHHMA PTEDEFDCKA WAYFSDVDLE
KDVHSGLIGP LLICRANTLN AAHGRQVTVQ EFALFFTIFD ETKSWYFTEN VERNCRAPCH
LQMEDPTLKE NYRFHAINGY VMDTLPGLVM AQNQRIRWYL LSMGSNENIH SIHFSGHVFS
VRKKEEYKMA VYNLYPGVFE TVEMLPSKVG IWRIECLIGE HLQAGMSTTF LVYSKECQAP
LGMASGRIRD FQITASGQYG QWAPKLARLH YSGSINAWST KDPHSWIKVD LLAPMIIHGI
MTQGARQKFS SLYISQFIIM YSLDGRNWQS YRGNSTGTLM VFFGNVDASG IKHNIFNPPI
VARYIRLHPT HYSIRSTLRM ELMGCDLNSC SMPLGMQNKA ISDSQITASS HLSNIFATWS
PSQARLHLQG RTNAWRPRVS SAEEWLQVDL QKTVKVTGIT TQGVKSLLSS MYVKEFLVSS
SQDGRRWTLF LQDGHTKVFQ GNQDSSTPVV NALDPPLFTR YLRIHPTSWA QHIALRLEVL
GCEAQDLY
(Disulfide bridge: 154-180, 249-330, 528-554, 630-711, 948-974, 1015-1019, 1137-1285, 1290-1442)
  Type
Peptide
Class
Cardiovascular agent
 DG02016  Hemostatics
  DG02013  Blood coagulation factor
  DG02014  Blood coagulation accelerant
   DG02013  Blood coagulation factor
Remark
ATC code: B02BD02
Chemical structure group: DG00170
Product (DG00170): D08798<JP> D05409<JP> D10227<JP> D10539<JP> D10758<JP> D10759<JP> D10760<JP> D10771<JP> D10818<JP>
Efficacy
Bleeding suppressant
Comment
Therapeutic area: Hemophilia A
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B02 ANTIHEMORRHAGICS
   B02B VITAMIN K AND OTHER HEMOSTATICS
    B02BD Blood coagulation factors
     B02BD02 Coagulation factor VIII
      D10831  Susoctocog alfa (INN)
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D10831
Other DBs
CAS: 1339940-90-7
PubChem: 319902631
LinkDB

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