KEGG   DRUG: Epoetin zetaHelp
Entry
D10847                      Drug                                   

Name
Epoetin zeta (INN);
Retacrit (TN);
Silapo (TN)
Formula
C809H1301N229O240S5
Exact mass
18224.5242
Mol weight
18235.7015
Sequence
APPRLICDSR VLERYLLEAK EAENITTGCA EHCSLNENIT VPDTKVNFYA WKRMEVGQQA
VEVWQGLALL SEAVLRGQAL LVNSSQPWEP LQLHVDKAVS GLRSLTTLLR ALGAQKEAIS
PPDAASAAPL RTITADTFRK LFRVYSNFLR GKLKLYTGEA CRTGD
(Disulfide bridge: 7-161, 29-33)
  Type
Peptide
Remark
ATC code: B03XA01
Chemical structure group: DG00177
Product (DG00177): D03231<JP/US> D03232<JP>
Efficacy
Anti-anemic, Antineoplastic
Target
EPOR [HSA:2057] [KO:K05079]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04630  JAK-STAT signaling pathway
hsa04640  Hematopoietic cell lineage
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B03 ANTIANEMIC PREPARATIONS
   B03X OTHER ANTIANEMIC PREPARATIONS
    B03XA Other antianemic preparations
     B03XA01 Erythropoietin
      D10847  Epoetin zeta (INN)
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokine receptors
   CSF and other factor receptors
    EPOR
     D10847  Epoetin zeta (INN)
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D10847
BRITE hierarchy
Other DBs
CAS: 604802-70-2
PubChem: 319902647
LinkDB All DBs

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