KEGG   DRUG: Nusinersen
Entry
D10881                      Drug                                   
Name
Nusinersen (USAN/INN);
Spinraza (TN)
Formula
C234H340N61O128P17
Exact mass
6578.7511
Mol weight
6582.09
Remark
ATC code: M09AX07
Chemical structure group: DG02002
Product (DG02002): D10791<JP/US>
Efficacy
Translation inhibitor
  Type
Antisense oligonucleotide
Comment
Treatment of spinal muscular atrophy
Target
SMN2 [HSA:6607] [KO:K13129] (pre-mRNA intron7)
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 M MUSCULO-SKELETAL SYSTEM
  M09 OTHER DRUGS FOR DISORDERS OF THE MUSCULO-SKELETAL SYSTEM
   M09A OTHER DRUGS FOR DISORDERS OF THE MUSCULO-SKELETAL SYSTEM
    M09AX Other drugs for disorders of the musculo-skeletal system
     M09AX07 Nusinersen
      D10881  Nusinersen (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Not elsewhere classified
  Genetic information processing
   Spliceosome
    SMN2
     D10881  Nusinersen (USAN/INN)
Other DBs
CAS: 1258984-36-9
PubChem: 328082973
LinkDB

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