KEGG   DRUG: Abaloparatide
Entry
D10885                      Drug                                   
Name
Abaloparatide (USAN/INN);
Tymlos (TN)
Product
TYMLOS (Radius Health)
Formula
C174H300N56O49
Exact mass
3958.2705
Mol weight
3960.59
Sequence
Ala Val Ser Glu His Gln Leu Leu His Asp Lys Gly Lys Ser Ile Gln
Asp Leu Arg Arg Arg Glu Leu Leu Glu Lys Leu Leu Aib Lys Leu His
Thr Ala
  Type
Peptide
Class
Hormonal agent
 DG01661  Parathyroid hormone and parathyroid hormone-related protein analog
Musculo-skeletal system agent
 DG03232  Osteoporosis agent
Remark
ATC code: H05AA04
Chemical structure group: DG03050
Product (DG03050): D10885<US> D11563<JP>
Efficacy
Osteoporosis agent, Osteogenesis stimulant, Parathyroid hormone receptor 1 agonist
  Disease
Osteoporosis [DS:H01593]
Comment
Human parathyroid hormone related peptide [HSA:5744] [KO:K22608] analog (hPTHrP)
Treatment of osteoporosis
Target
PTH1R [HSA:5745] [KO:K04585]
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H05 CALCIUM HOMEOSTASIS
   H05A PARATHYROID HORMONES AND ANALOGUES
    H05AA Parathyroid hormones and analogues
     H05AA04 Abaloparatide
      D10885  Abaloparatide (USAN/INN) <US>
USP drug classification [BR:br08302]
 Metabolic Bone Disease Agents
  Calcium Regulating Hormones
   Abaloparatide
    D10885  Abaloparatide (USAN/INN)
Drug groups [BR:br08330]
 Hormonal agent
  DG01661  Parathyroid hormone and parathyroid hormone-related protein analog
   DG03050  Abaloparatide
    D10885  Abaloparatide
 Musculo-skeletal system agent
  DG03232  Osteoporosis agent
   DG03050  Abaloparatide
    D10885  Abaloparatide
Drug classes [BR:br08332]
 Musculo-skeletal system agent
  DG03232  Osteoporosis agent
   D10885  Abaloparatide
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Secretin receptor family
   Parathyroid hormone
    PTH1R
     D10885  Abaloparatide (USAN/INN) <US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D10885
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D10885
Drug groups [BR:br08330]
 Hormonal agent
  DG01661  Parathyroid hormone and parathyroid hormone-related protein analog
   DG03050  Abaloparatide
 Musculo-skeletal system agent
  DG03232  Osteoporosis agent
   DG03050  Abaloparatide
Other DBs
CAS: 247062-33-5
PubChem: 336445203
LinkDB

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