| Entry |
|
|---|
| Name |
Neflamapimod (USAN/INN) |
|---|
| Formula |
C19H9Cl2F2N3OS
|
|---|
| Exact mass |
434.9811
|
|---|
| Mol weight |
436.26
|
|---|
| Structure |
|
|---|
| Efficacy |
Anti-inflammatory, Mitogen-activated protein kinase inhibitor |
|---|
| Target |
|
|---|
| Pathway |
| hsa04750 | Inflammatory mediator regulation of TRP channels |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Protein kinases
Serine/threonine kinases
CMGC group
P38
D10959 Neflamapimod (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 28
1 C8x C 14.2100 -15.3300
2 C8y C 14.2100 -16.7300
3 N5x N 15.4224 -17.4300
4 N4y N 16.6349 -16.7300
5 C8y C 16.6349 -15.3300
6 C8x C 15.4224 -14.6300
7 C8x C 17.8473 -17.4300
8 N5x N 19.0597 -16.7300
9 C8y C 19.0597 -15.3300
10 C8y C 17.8473 -14.6300
11 S2a S 12.9976 -17.4300
12 C8y C 11.8021 -16.7396
13 C8x C 11.8020 -15.3303
14 C8x C 10.5896 -14.6303
15 C8y C 9.3772 -15.3303
16 C8x C 9.3772 -16.7397
17 C8y C 10.5896 -17.4396
18 X F 10.5895 -18.8299
19 X F 8.1667 -14.6315
20 O5x O 20.2573 -14.6385
21 C8y C 17.8473 -13.2300
22 C8y C 19.0618 -12.5288
23 C8x C 19.0618 -11.1288
24 C8x C 17.8493 -10.4288
25 C8x C 16.6349 -11.1300
26 C8y C 16.6349 -12.5300
27 X Cl 15.4414 -13.2193
28 X Cl 20.2583 -13.2198
BOND 31
1 1 2 1
2 2 3 2
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 2
9 8 9 1
10 9 10 1
11 5 10 2
12 2 11 1
13 11 12 1
14 12 13 2
15 13 14 1
16 14 15 2
17 15 16 1
18 16 17 2
19 12 17 1
20 17 18 1
21 15 19 1
22 9 20 2
23 10 21 1
24 21 22 2
25 22 23 1
26 23 24 2
27 24 25 1
28 25 26 2
29 21 26 1
30 26 27 1
31 22 28 1
|
|---|
