KEGG   DRUG: Patisiran
Entry
D11116                      Drug                                   

Name
Patisiran (USAN/INN)
Formula
C412H520N148O290P40
Exact mass
13417.9997
Mol weight
13424.3053
Remark
ATC code: N07XX12
Chemical structure group: DG02955
Product (DG02955): D10794<JP/US>
Efficacy
Gene expression regulator
Comment
RNA interference (RNAi) drug
Treatment of hereditary ATTR amyloidosis
Target
TTR [HSA:7276] [KO:K20731] (mRNA)
  Pathway
hsa04918  Thyroid hormone synthesis
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N07 OTHER NERVOUS SYSTEM DRUGS
   N07X OTHER NERVOUS SYSTEM DRUGS
    N07XX Other nervous system drugs
     N07XX12 Patisiran
      D11116  Patisiran (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Other transporters
   Others
    TTR
     D11116  Patisiran (USAN/INN)
Other DBs
CAS: 1420706-45-1
PubChem: 376219040
LinkDB

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