KEGG   DRUG: PegbelferminHelp
Entry
D11512                      Drug                                   

Name
Pegbelfermin (USAN)
Formula
C874H1352N242O264S3. (C2H4O)n
Sequence
MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK
PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYFS EAHGLPLHLP
GNKSPHRDPA PRGPARFLPL PGLPPAPPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY
AS
(Disulfide bridge: 76-94)
  Type
Peptide
Efficacy
Antifibrotic, Fibroblast growth factor replacement
Comment
Treatment of liver fibrosis; NASH (non-alcoholic steatohepatitis)
Target
FGF21 [HSA:26291] [KO:K22429]
Brite
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokines
   Growth factors (RTK-binding)
    FGF21
     D11512  Pegbelfermin (USAN)
BRITE hierarchy
Other DBs
CAS: 2089039-22-3
PubChem: 384585488
LinkDB All DBs

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