| Entry |
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| Name |
Infigratinib (USAN/INN) |
|---|
| Formula |
C26H31Cl2N7O3
|
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| Exact mass |
559.1865
|
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| Mol weight |
560.47
|
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| Structure |
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| Class |
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG03208 FGFR inhibitor
|
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| Remark |
|
|---|
| Efficacy |
Antineoplastic, Angiogenesis inhibitor |
|---|
| Target |
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| Pathway |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 ANTINEOPLASTIC AGENTS
L01E PROTEIN KINASE INHIBITORS
L01EN Fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitors
L01EN03 Infigratinib
D11589 Infigratinib (USAN/INN)
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG03208 FGFR inhibitor
DG03062 Infigratinib
D11589 Infigratinib
Target-based classification of drugs [BR:br08310]
Protein kinases
Receptor tyrosine kinases (RTK)
FGFR family
FGFR1 (CD331)
D11589 Infigratinib (USAN/INN)
FGFR2 (CD332)
D11589 Infigratinib (USAN/INN)
FGFR3 (CD333)
D11589 Infigratinib (USAN/INN)
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG03208 FGFR inhibitor
DG03062 Infigratinib
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 38
1 N1y N 5.3900 -15.8900
2 C1x C 5.3900 -17.2900
3 C1x C 6.6024 -17.9900
4 N1y N 7.8149 -17.2900
5 C1x C 7.8149 -15.8900
6 C1x C 6.6024 -15.1900
7 C1b C 4.1776 -15.1900
8 C1a C 2.9821 -15.8804
9 C8y C 9.0460 -18.0010
10 C8x C 9.0457 -19.3899
11 C8x C 10.2580 -20.0902
12 C8y C 11.4706 -19.3905
13 C8x C 11.4709 -18.0016
14 C8x C 10.2586 -17.3013
15 N1b N 12.6897 -20.0947
16 C8y C 13.8894 -19.4023
17 C8x C 15.0743 -20.0867
18 C8y C 16.2869 -19.3870
19 N5x N 16.2872 -17.9870
20 C8x C 15.1023 -17.3025
21 N5x N 13.8897 -18.0023
22 N1c N 17.5177 -20.0981
23 C5a C 18.7204 -19.4041
24 C1a C 17.5173 -21.4899
25 N1b N 19.9038 -20.0877
26 O5a O 18.7211 -17.9903
27 C8y C 21.0975 -19.3988
28 C8y C 22.2853 -20.0850
29 C8y C 23.4979 -19.3853
30 C8x C 23.4983 -17.9853
31 C8y C 22.3104 -17.2991
32 C8y C 21.0978 -17.9988
33 X Cl 22.2851 -21.4898
34 O2a O 22.3106 -15.8901
35 C1a C 23.5377 -15.1818
36 O2a O 24.7287 -20.0964
37 C1a C 25.9300 -19.4032
38 X Cl 19.8610 -17.2841
BOND 41
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1
8 7 8 1
9 4 9 1
10 9 10 2
11 10 11 1
12 11 12 2
13 12 13 1
14 13 14 2
15 9 14 1
16 12 15 1
17 15 16 1
18 16 17 2
19 17 18 1
20 18 19 2
21 19 20 1
22 20 21 2
23 16 21 1
24 18 22 1
25 22 23 1
26 22 24 1
27 23 25 1
28 23 26 2
29 25 27 1
30 27 28 2
31 28 29 1
32 29 30 2
33 30 31 1
34 31 32 2
35 27 32 1
36 28 33 1
37 31 34 1
38 34 35 1
39 29 36 1
40 36 37 1
41 32 38 1
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