| Entry |
|
|---|
| Name |
Remibrutinib (JAN/USAN/INN) |
|---|
| Formula |
C27H27F2N5O3
|
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| Exact mass |
507.2082
|
|---|
| Mol weight |
507.53
|
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| Structure |
|
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| Class |
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG02022 BTK inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Autoimmune disease treatment, Bruton's tyrosine kinase inhibitor |
|---|
| Comment |
Treatment of chronic spontaneous urticaria
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04662 | B cell receptor signaling pathway |
| hsa04664 | Fc epsilon RI signaling pathway |
|
|---|
| Interaction |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L04 IMMUNOSUPPRESSANTS
L04A IMMUNOSUPPRESSANTS
L04AA Selective immunosuppressants
L04AA60 Remibrutinib
D12285 Remibrutinib (JAN/USAN/INN)
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG02022 BTK inhibitor
D12285 Remibrutinib
Target-based classification of drugs [BR:br08310]
Protein kinases
Non-receptor tyrosine kinases
TEC family
BTK
D12285 Remibrutinib (JAN/USAN/INN)
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 37
1 C8y C 10.9200 -14.7700
2 C8y C 10.9200 -13.3700
3 N5x N 9.7300 -12.6700
4 C8x C 8.4700 -13.3700
5 N5x N 8.4700 -14.7700
6 C8y C 9.7300 -15.4700
7 N1a N 9.7300 -16.8700
8 O2a O 12.1100 -15.4700
9 C1b C 12.1100 -16.8700
10 C1b C 13.3000 -17.5700
11 C8y C 12.1100 -12.6700
12 C8y C 13.3000 -13.3700
13 C8y C 14.5600 -12.6700
14 C8x C 14.5600 -11.2700
15 C8y C 13.3700 -10.5700
16 C8x C 12.1100 -11.2700
17 C1a C 13.3000 -14.7000
18 X F 13.3700 -9.1700
19 N1b N 15.7500 -13.3700
20 C5a C 16.9400 -12.6700
21 C8y C 18.1300 -13.3700
22 O5a O 16.9400 -11.2700
23 C8x C 18.1300 -14.7700
24 C8x C 19.3900 -15.4700
25 C8y C 20.5800 -14.7700
26 C8x C 20.5800 -13.3700
27 C8y C 19.3900 -12.6700
28 X F 19.3900 -11.2700
29 C1y C 21.7700 -15.4700
30 C1x C 23.1700 -15.4700
31 C1x C 22.4700 -16.6600
32 N1c N 14.4900 -16.8700
33 C5a C 15.6800 -17.5700
34 C1a C 14.4900 -15.4700
35 C2b C 16.8700 -16.8700
36 O5a O 15.6800 -18.9700
37 C2a C 18.0600 -17.5700
BOND 40
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 6 7 1
8 1 8 1
9 8 9 1
10 9 10 1
11 2 11 1
12 11 12 2
13 12 13 1
14 13 14 2
15 14 15 1
16 15 16 2
17 11 16 1
18 12 17 1
19 15 18 1
20 13 19 1
21 19 20 1
22 20 21 1
23 20 22 2
24 21 23 2
25 23 24 1
26 24 25 2
27 25 26 1
28 26 27 2
29 21 27 1
30 27 28 1
31 25 29 1
32 30 29 1
33 29 31 1
34 31 30 1
35 10 32 1
36 32 33 1
37 32 34 1
38 33 35 1
39 33 36 2
40 35 37 2
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