KEGG   DRUG: ナプロキセン
エントリ  
D00118                      Drug                                   

一般名   
ナプロキセン (JP17);
Naproxen (JP17/USP/INN)
商品名   
米国の商品 
  後発品
NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (American Health Packaging), NAPROXEN (American Health Packaging), NAPROXEN (Amneal Pharmaceuticals LLC), NAPROXEN (Amneal Pharmaceuticals NY LLC), NAPROXEN (Amneal Pharmaceuticals of New York LLC), NAPROXEN (Aphena Pharma Solutions - Tennessee), NAPROXEN (Aphena Pharma Solutions - Tennessee), NAPROXEN (Aphena Pharma Solutions - Tennessee), NAPROXEN (Asclemed USA), NAPROXEN (Aurobindo Pharma Limited), NAPROXEN (AvKARE), NAPROXEN (AvKARE), NAPROXEN (AvPAK), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Cadila Healthcare Limited), NAPROXEN (Cipla USA), NAPROXEN (Cipla USA), NAPROXEN (Clinical Solutions Wholesale), NAPROXEN (DIRECT RX), NAPROXEN (DIRECT RX), NAPROXEN (DIRECT RX), NAPROXEN (Denton Pharma), NAPROXEN (Denton Pharma), NAPROXEN (Denton Pharma), NAPROXEN (Denton Pharma), NAPROXEN (Direct RX), NAPROXEN (DirectRX), NAPROXEN (Direct_Rx), NAPROXEN (Direct_Rx), NAPROXEN (Direct_Rx), NAPROXEN (Direct_Rx), NAPROXEN (Direct_Rx), NAPROXEN (Exelan Pharmaceuticals), NAPROXEN (Lake Erie Medical DBA Quality Care Products LLC), NAPROXEN (Lake Erie Medical DBA Quality Care Products LLC), NAPROXEN (Medsource Pharmaceuticals), NAPROXEN (NCS HealthCare of KY), NAPROXEN (Northwind Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (PD-Rx Pharmaceuticals), NAPROXEN (PD-Rx Pharmaceuticals), NAPROXEN (PD-Rx Pharmaceuticals), NAPROXEN (PD-Rx Pharmaceuticals), NAPROXEN (PD-Rx Pharmaceuticals), NAPROXEN (PD-Rx Pharmaceuticals), NAPROXEN (PD-Rx Pharmaceuticals), NAPROXEN (Palmetto Pharmaceuticals), NAPROXEN (Preferred Pharmaceuticals), NAPROXEN (Preferred Pharmaceuticals), NAPROXEN (Preferred Pharmaceuticals), NAPROXEN (Preferred Pharmaceuticals), NAPROXEN (Preferred Pharmaceuticals), NAPROXEN (Preferred Pharmaceuticals), NAPROXEN (Preferred Pharmaceuticals), NAPROXEN (Preferred Pharmaceuticals), NAPROXEN (Proficient Rx LP), NAPROXEN (Proficient Rx LP), NAPROXEN (Proficient Rx LP), NAPROXEN (Proficient Rx LP), NAPROXEN (Proficient Rx LP), NAPROXEN (Proficient Rx LP), NAPROXEN (QPharma), NAPROXEN (QPharma), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN (RedPharm Drug), NAPROXEN (RedPharm Drug), NAPROXEN (RedPharm Drug), NAPROXEN (RedPharm Drug), NAPROXEN (RedPharm Drug), NAPROXEN (RedPharm Drug), NAPROXEN (ScieGen Pharmaceuticals), NAPROXEN (St. Mary's Medical Park Pharmacy), NAPROXEN (St. Mary's Medical Park Pharmacy), NAPROXEN (TIME CAP LABORATORIES), NAPROXEN (Teva Pharmaceuticals USA), NAPROXEN (Unit Dose Services), NAPROXEN (Unit Dose Services), NAPROXEN (Unit Dose Services), NAPROXEN (Virtus Pharmaceuticals), NAPROXEN (Zydus Pharmaceuticals (USA)), NAPROXEN (medsource pharmaceuticals), NAPROXEN (medsource pharmaceuticals), NAPROXEN (medsource pharmaceuticals), NAPROSYN (Advanced Rx Pharmacy of Tennessee), NAPROSYN (Advanced Rx Pharmacy of Tennessee), NAPROSYN (Advanced Rx Pharmacy of Tennessee), NAPROSYN (Advanced Rx Pharmacy of Tennessee), NAPROXEN SODIUM (Glenmark Pharmaceuticals Limited)
組成式   
C14H14O3
質量    
230.0943
分子量   
230.2592
構造式   
Simcomp   
クラス   
抗炎症薬
 DG01908  プロピオン酸系抗炎症薬
 DG01504  非ステロイド性抗炎症薬 (NSAID)
  DG01908  プロピオン酸系抗炎症薬
コード   
同一コード: C01517
薬効分類: 1149
ATCコード: G02CC02 M01AE02 M02AA12
化学構造グループ: DG00455
商品 (DG00455): D00118<JP/US> D00970<US>
商品 (mixture): D11576<US>
効能    
鎮痛薬, 抗炎症薬, 解熱薬, シクロオキシゲナーゼ阻害薬
  疾患
関節リウマチ [DS:H00630]
痛風発作 [DS:H01532]
強直性脊椎炎 [DS:H01674]
帯状疱疹 [DS:H00366]
コメント  
プロピオン酸誘導体
ターゲット 
PTGS1 (COX1) [HSA:5742] [KO:K00509]
PTGS2 (COX2) [HSA:5743] [KO:K11987]
  パスウェイ
hsa00590  アラキドン酸の代謝
相互作用  

構造マップ 
map07048  抗片頭痛薬
map07114  ナフタレンファミリー
map07219  シクロオキシナーゼ (COX) 阻害薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 1  神経系及び感覚器官用医薬品
  11  中枢神経系用薬
   114  解熱鎮痛消炎剤
    1149  その他の解熱鎮痛消炎剤
     D00118  ナプロキセン (JP17)
医療用医薬品のATC分類 [BR:jp08303]
 G 泌尿生殖器系と性ホルモン
  G02 その他の婦人科用薬
   G02C その他の婦人科用薬
    G02CC 膣内投与用抗炎症製剤
     G02CC02 ナプロキセン
      D00118  ナプロキセン (JP17) <JP/US>
 M 筋骨格系
  M01 抗炎症及び抗リウマチ製剤
   M01A 抗炎症及び抗リウマチ製剤、非ステロイド系
    M01AE プロピオン酸誘導体
     M01AE02 ナプロキセン
      D00118  ナプロキセン (JP17) <JP/US>
  M02 関節・筋肉痛用局所薬剤
   M02A 関節・筋肉痛用局所薬剤
    M02AA 抗炎症製剤、局所用非ステロイド系
     M02AA12 ナプロキセン
      D00118  ナプロキセン (JP17) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 鎮痛薬
  非ステロイド系抗炎症薬
   ナプロキセン
    D00118  ナプロキセン (JP17)
ターゲットに基づく医薬品分類 [BR:jp08310]
 酵素
  オキシドレダクターゼ (EC1)
   プロスタグランジン合成酵素
    PTGS1 (COX1)
     D00118  ナプロキセン (JP17) <JP/US>
    PTGS2 (COX2)
     D00118  ナプロキセン (JP17) <JP/US>
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D00118  ナプロキセン
リンク   
CAS: 22204-53-1
PubChem: 7847186
ChEBI: 7476
ChEMBL: CHEMBL154
DrugBank: DB00788
PDB-CCD: NPS[PDBj]
LigandBox: D00118
日化辞: J9.289D
LinkDB    

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