KEGG   DRUG: アテノロール
エントリ  
D00235                      Drug                                   

一般名   
アテノロール (JP17);
Atenolol (JP17/USP/INN)
商品名   
  後発品
米国の商品 
  後発品
ATENOLOL (A-S Medication Solutions), ATENOLOL (A-S Medication Solutions), ATENOLOL (A-S Medication Solutions), ATENOLOL (A-S Medication Solutions), ATENOLOL (A-S Medication Solutions), ATENOLOL (A-S Medication Solutions), ATENOLOL (A-S Medication Solutions), ATENOLOL (A-S Medication Solutions), ATENOLOL (Aphena Pharma Solutions - Tennessee), ATENOLOL (Aphena Pharma Solutions - Tennessee), ATENOLOL (Aphena Pharma Solutions - Tennessee), ATENOLOL (Apotheca), ATENOLOL (Apotheca), ATENOLOL (Apotheca), ATENOLOL (Aurobindo Pharma Limited), ATENOLOL (AvKARE), ATENOLOL (Bryant Ranch Prepack), ATENOLOL (Bryant Ranch Prepack), ATENOLOL (Bryant Ranch Prepack), ATENOLOL (Bryant Ranch Prepack), ATENOLOL (Bryant Ranch Prepack), ATENOLOL (Bryant Ranch Prepack), ATENOLOL (Bryant Ranch Prepack), ATENOLOL (Bryant Ranch Prepack), ATENOLOL (Bryant Ranch Prepack), ATENOLOL (Bryant Ranch Prepack), ATENOLOL (Cadila Healthcare Limited), ATENOLOL (Cardinal Health), ATENOLOL (Contract Pharmacy Services-PA), ATENOLOL (DIRECT RX), ATENOLOL (DIRECT RX), ATENOLOL (Denton Pharma), ATENOLOL (Denton Pharma), ATENOLOL (Denton Pharma), ATENOLOL (Denton Pharma), ATENOLOL (Denton Pharma), ATENOLOL (Denton Pharma), ATENOLOL (Direct Rx), ATENOLOL (Direct_Rx), ATENOLOL (Direct_Rx), ATENOLOL (Direct_Rx), ATENOLOL (Direct_Rx), ATENOLOL (Golden State Medical Supply), ATENOLOL (Lake Erie Medical DBA Quality Care Products LLC), ATENOLOL (Legacy Pharmaceutical Packaging), ATENOLOL (Mylan Institutional), ATENOLOL (Mylan Pharmaceuticals), ATENOLOL (NCS HealthCare of KY), ATENOLOL (NuCare Pharmaceuticals), ATENOLOL (NuCare Pharmaceuticals), ATENOLOL (NuCare Pharmaceuticals), ATENOLOL (NuCare Pharmaceuticals), ATENOLOL (NuCare Pharmaceuticals), ATENOLOL (NuCare Pharmaceuticals), ATENOLOL (NuCare Pharmaceuticals), ATENOLOL (NuCare Pharmaceuticals), ATENOLOL (NuCare Pharmaceuticals), ATENOLOL (NuCare Pharmaceuticals), ATENOLOL (NuCare Pharmaceuticals), ATENOLOL (NuCare Pharmaceuticals), ATENOLOL (NuCare Pharmaceuticals), ATENOLOL (PD-Rx Pharmaceuticals), ATENOLOL (PD-Rx Pharmaceuticals), ATENOLOL (PD-Rx Pharmaceuticals), ATENOLOL (PD-Rx Pharmaceuticals), ATENOLOL (Preferred Pharmaceuticals), ATENOLOL (Preferred Pharmaceuticals), ATENOLOL (Preferred Pharmaceuticals), ATENOLOL (Preferred Pharmaceuticals), ATENOLOL (Preferred Pharmaceuticals), ATENOLOL (Preferred Pharmaceuticals), ATENOLOL (Preferred Pharmaceuticals), ATENOLOL (Proficient Rx LP), ATENOLOL (Proficient Rx LP), ATENOLOL (Proficient Rx LP), ATENOLOL (Proficient Rx LP), ATENOLOL (Proficient Rx LP), ATENOLOL (Proficient Rx LP), ATENOLOL (Proficient Rx LP), ATENOLOL (QPharma), ATENOLOL (Quality Care Products), ATENOLOL (REMEDYREPACK), ATENOLOL (REMEDYREPACK), ATENOLOL (REMEDYREPACK), ATENOLOL (REMEDYREPACK), ATENOLOL (RedPharm Drug), ATENOLOL (RedPharm Drug), ATENOLOL (RedPharm Drug), ATENOLOL (RedPharm Drug), ATENOLOL (RedPharm Drug), ATENOLOL (RedPharm Drug), ATENOLOL (RedPharm Drug), ATENOLOL (Rising Pharmaceuticals), ATENOLOL (Sandoz), ATENOLOL (St Mary's Medical Park Pharmacy), ATENOLOL (St. Mary's Medical Park Pharmacy), ATENOLOL (St. Mary's Medical Park Pharmacy), ATENOLOL (St. Mary's Medical Park Pharmacy), ATENOLOL (St. Mary's Medical Park Pharmacy), ATENOLOL (St. Mary's Medical Park Pharmacy), ATENOLOL (Teva Pharmaceuticals USA), ATENOLOL (Unichem Pharmaceuticals (USA)), ATENOLOL (Unit Dose Services), ATENOLOL (Unit Dose Services), ATENOLOL (Zydus Pharmaceuticals (USA)), ATENOLOL (direct rx), ATENOLOL (direct rx)
組成式   
C14H22N2O3
質量    
266.163
分子量   
266.3361
構造式   
Simcomp   
クラス   
循環器系用薬
 DG01653  抗不整脈薬
  DG01806  クラスII抗不整脈薬
 DG01466  アドレナリン受容体拮抗薬
  DG01464  β-アドレナリン受容体拮抗薬
   DG01461  β1-アドレナリン受容体拮抗薬
代謝酵素基質薬
 DG01644  CYP2D6基質薬
コード   
薬効分類: 2123
ATCコード: C07AB03
商品: D00235<JP/US>
商品 (mixture): D10592<US>
効能    
抗不整脈薬, 血圧降下薬, 血管拡張薬, β1遮断薬
  疾患
本態性高血圧症 [DS:H01633]
狭心症 [DS:H01632]
コメント  
プロプラノロール誘導体
ターゲット 
ADRB1 [HSA:153] [KO:K04141]
  パスウェイ
hsa04080  神経刺激性リガンドとレセプターの相互作用
hsa04261  心筋細胞におけるアドレナリンシグナル伝達
代謝    
Enzyme: CYP2D6 [HSA:1565]
相互作用  

構造マップ 
map07037  抗不整脈薬
map07048  抗片頭痛薬
map07214  β-アドレナリン受容体の作動薬と拮抗薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 2  個々の器官系用医薬品
  21  循環器官用薬
   212  不整脈用剤
    2123  β−遮断剤
     D00235  アテノロール (JP17)
医療用医薬品のATC分類 [BR:jp08303]
 C 循環器系
  C07 ベータ遮断薬
   C07A ベータ遮断薬
    C07AB ベータ遮断薬、選択型
     C07AB03 アテノロール
      D00235  アテノロール (JP17) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 心血管治療薬
  ベータアドレナリン遮断薬
   ベータ1選択的
    アテノロール
     D00235  アテノロール (JP17)
ターゲットに基づく医薬品分類 [BR:jp08310]
 Gタンパク質共役受容体
  ロドプシンファミリー
   アドレナリン
    ADRB1
     D00235  アテノロール (JP17) <JP/US>
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D00235  アテノロール
薬物代謝酵素とトランスポーター [jp08309.html]
 薬物代謝酵素
  D00235
リンク   
CAS: 29122-68-7
PubChem: 7847302
ChEBI: 2904
ChEMBL: CHEMBL24
DrugBank: DB00335
LigandBox: D00235
日化辞: J3.170D
LinkDB    

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