KEGG   DRUG: ロピニロール塩酸塩Help
エントリ  
D00784                      Drug                                   

一般名   
ロピニロール塩酸塩 (JAN);
塩酸ロピニロール;
Ropinirole hydrochloride (JAN/USAN)
商品名   
  後発品
米国の商品 
  後発品
ROPINIROLE (Actavis Pharma), ROPINIROLE (Alembic Pharmaceuticals Limited), ROPINIROLE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), ROPINIROLE (Aphena Pharma Solutions - Tennessee), ROPINIROLE (Apotex Corp.), ROPINIROLE (Bryant Ranch Prepack), ROPINIROLE (Bryant Ranch Prepack), ROPINIROLE HYDROCHLORIDE (Bryant Ranch Prepack), ROPINIROLE (Bryant Ranch Prepack), ROPINIROLE (Carilion Materials Management), ROPINIROLE (Carilion Materials Management), ROPINIROLE (Carilion Materials Management), ROPINIROLE (Dispensing Solutions), ROPINIROLE (Dr. Reddys Laboratories Limited), ROPINIROLE (Glenmark Pharmaceuticals), ROPINIROLE HYDROCHLORIDE (Golden State Medical Supply), ROPINIROLE (Lake Erie Medical DBA Quality Care Products LLC), ROPINIROLE HYDROCHLORIDE (Mylan Pharmaceuticals), ROPINIROLE (Sandoz), ROPINIROLE (Trigen Laboratories), ROPINIROLE (Unit Dose Services), ROPINIROLE (West-Ward Pharmaceuticals Corp.), ROPINIROLE HYDROCHLORIDE (Aidarex Pharmaceuticals LLC), ROPINIROLE HYDROCHLORIDE (Alembic Pharmaceuticals), ROPINIROLE HYDROCHLORIDE (Alembic Pharmaceuticals Limited), ROPINIROLE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), ROPINIROLE HYDROCHLORIDE (Avera McKennan Hospital), ROPINIROLE HYDROCHLORIDE (Avera McKennan Hospital), ROPINIROLE HYDROCHLORIDE (Avera McKennan Hospital), ROPINIROLE HYDROCHLORIDE (Avera McKennan Hospital), ROPINIROLE HYDROCHLORIDE (Bryant Ranch Prepack), ROPINIROLE HYDROCHLORIDE (Bryant Ranch Prepack), ROPINIROLE HYDROCHLORIDE (Bryant Ranch Prepack), ROPINIROLE HYDROCHLORIDE (Bryant Ranch Prepack), ROPINIROLE HYDROCHLORIDE (Bryant Ranch Prepack), ROPINIROLE HYDROCHLORIDE (Bryant Ranch Prepack), ROPINIROLE HYDROCHLORIDE (Cadila Healthcare Limited), ROPINIROLE HYDROCHLORIDE (Dispensing Solutions), ROPINIROLE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), ROPINIROLE HYDROCHLORIDE (Major Pharmaceuticals), ROPINIROLE HYDROCHLORIDE (Mylan Pharmaceuticals), ROPINIROLE HYDROCHLORIDE (NCS HealthCare of KY), ROPINIROLE HYDROCHLORIDE (Physicians Total Care), ROPINIROLE HYDROCHLORIDE (Rebel Distributors Corp), ROPINIROLE HYDROCHLORIDE (Rebel Distributors Corp), ROPINIROLE HYDROCHLORIDE (Solco healthcare U.S.), ROPINIROLE HYDROCHLORIDE (Wockhardt Limited), ROPINIROLE HYDROCHLORIDE (Wockhardt Limited), ROPINIROLE HYDROCHLORIDE (Wockhardt USA LLC.), ROPINIROLE HYDROCHLORIDE (Wockhardt USA LLC.), ROPINIROLE HYDROCHLORIDE (Zhejiang Huahai Pharmaceutical), ROPINIROLE HYDROCHLORIDE (Zydus Pharmaceuticals (USA))
組成式   
C16H24N2O. HCl
質量    
296.1655
分子量   
296.8355
構造式   
Mol fileKCF fileDB search
Simcomp    SIMCOMP
クラス   
精神神経系用薬
 DG01472  ドパミン作動薬
  DG01468  ドパミンD2-受容体作動薬
 DG01967  抗パーキンソン病薬
Cyp 基質
 DG01892  CYP1A2により代謝される薬剤
コード   
薬効分類: 1169
ATCコード: N04BC04
化学構造グループ: DG00862
商品 (DG00862): D00784<JP/US>
効能    
パーキンソン病治療薬, ドパミン受容体作動薬
  疾患
パーキンソン病 [DS:H00057]
ターゲット 
DRD2 [HSA:1813] [KO:K04145]
DRD3 [HSA:1814] [KO:K04146]
DRD4 [HSA:1815] [KO:K04147]
  パスウェイ
hsa04080  神経刺激性リガンドとレセプターの相互作用
hsa04728  ドーパミン作動性シナプス
hsa05012  パーキンソン病
代謝    
Enzyme: CYP1A2 [HSA:1544]
相互作用  
Drug interaction
構造マップ 
map07057  抗パーキンソン病薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 1  神経系及び感覚器官用医薬品
  11  中枢神経系用薬
   116  抗パーキンソン剤
    1169  その他の抗パーキンソン剤
     D00784  ロピニロール塩酸塩 (JAN); 塩酸ロピニロール
医療用医薬品のATC分類 [BR:jp08303]
 N 神経系
  N04 抗パーキンソン薬
   N04B ドパミン系薬物
    N04BC ドパミン作動薬
     N04BC04 ロピニロール
      D00784  ロピニロール塩酸塩 (JAN) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 抗パーキンソン病薬
  ドパミン作動薬
   ロピニロール
    D00784  ロピニロール塩酸塩 (JAN)
Target-based classification of drugs  [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD2
     D00784  Ropinirole hydrochloride (JAN/USAN) <JP/US>
    DRD3
     D00784  Ropinirole hydrochloride (JAN/USAN) <JP/US>
    DRD4
     D00784  Ropinirole hydrochloride (JAN/USAN) <JP/US>
治療薬の医薬品クラス [jp08360.html]
 神経性疾患薬
  D00784
日本の新薬 [jp08318.html]
 新有効成分含有医薬品
  D00784
BRITE hierarchy
リンク   
CAS: 91374-20-8
PubChem: 7847849
ChEBI: 8889
ChEMBL: CHEMBL1200411
DrugBank: DB00268
LigandBox: D00784
LinkDB     All DBs

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