KEGG   DRUG: モルヒネ硫酸塩水和物
エントリ  
D00842                      Drug                                   

一般名   
モルヒネ硫酸塩水和物 (JP17);
Morphine sulfate (USP);
Morphine sulfate hydrate (JP17);
Morphine sulfate pentahydrate
商品名   
  後発品
米国の商品 
MORPHINE SULFATE (ATLANTIC BIOLOGICALS CORP.), MORPHINE SULFATE (ATLANTIC BIOLOGICALS CORP.), KADIAN (Actavis Pharma), KADIAN (Allergan), MORPHINE SULFATE (Bryant Ranch Prepack), MORPHINE SULFATE (DIRECTRX), MORPHABOND (Daiichi Sankyo), MORPHINE SULFATE (Fresenius Kabi USA), MORPHINE SULFATE (Fresenius Kabi USA), MORPHINE SULFATE (Fresenius Kabi), MORPHINE SULFATE (Hikma Pharmaceuticals USA), DURAMORPH (Hikma Pharmaceuticals USA), MORPHINE SULFATE (Hospira), MORPHINE SULFATE (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), MORPHINE SULFATE (Lake Erie Medical DBA Quality Care Products LLC), MORPHINE SULFATE (Lohxa), MORPHINE SULFATE (Meridian Medical Technologies), MORPHINE SULFATE (Precision Dose), MORPHINE SULFATE (Precision Dose), MORPHINE SULFATE (RedPharm Drug), MS CONTIN (Rhodes Pharmaceuticals L.P.), MORPHINE SULFATE (West-Ward Pharmaceuticals Corp), MORPHINE SULFATE (West-Ward Pharmaceuticals Corp.), ARYMO (Zyla Life Sciences US)
  後発品
MORPHINE SULFATE (ANI Pharmaceuticals), MORPHINE SULFATE (ATLANTIC BIOLOGICALS CORP.), MORPHINE SULFATE (Actavis Pharma), MORPHINE SULFATE (Actavis Pharma), MORPHINE SULFATE (Actavis Pharma), MORPHINE SULFATE (American Health Packaging), MORPHINE SULFATE (Amneal Pharmaceuticals of New York LLC), MORPHINE SULFATE (Bryant Ranch Prepack), MORPHINE SULFATE (Bryant Ranch Prepack), MORPHINE SULFATE (Bryant Ranch Prepack), MORPHINE SULFATE (Civica), MORPHINE SULFATE (Direct_Rx), MORPHINE SULFATE (Hi-Tech Pharmacal), MORPHINE SULFATE (Hikma Pharmaceuticals USA), MORPHINE SULFATE (Hospira), MORPHINE SULFATE (Lake Erie Medical DBA Quality Care Products LLC), MORPHINE SULFATE (Lake Erie Medical DBA Quality Care Products LLC), MORPHINE SULFATE (Lake Erie Medical DBA Quality Care Products LLC), MORPHINE SULFATE (Lake Erie Medical DBA Quality Care Products LLC), MORPHINE SULFATE (Lake Erie Medical DBA Quality Care Products LLC), MORPHINE SULFATE (Lake Erie Medical DBA Quality Care Products LLC), MORPHINE SULFATE (Lupin Pharmaceuticals), MORPHINE SULFATE (Major Pharmaceuticals), MORPHINE SULFATE (Mayne Pharma), MORPHINE SULFATE ORAL SOLUTION CII (Nostrum Laboratories), MORPHINE SULFATE (Novel Laboratories), MORPHINE SULFATE (Pharmaceutical Associates), MITIGO (Piramal Critical Care), MORPHINE SULFATE (Quality Care Products), MORPHINE SULFATE (Quality Care Products), MORPHINE SULFATE (RedPharm Drug), MORPHINE SULFATE (RedPharm Drug), MORPHINE SULFATE (Rhodes Pharmaceuticals L. P.), MORPHINE SULFATE (Rhodes Pharmaceuticals L.P.), MORPHINE SULFATE (Safecor Health), MORPHINE SULFATE (SpecGx LLC), MORPHINE SULFATE (SpecGx LLC), MORPHINE SULFATE (Sun Pharmaceutical Industries), MORPHINE SULFATE (Tris Pharma), MORPHINE SULFATE (Upsher-Smith Laboratories), MORPHINE SULFATE (Upsher-Smith Laboratories), MORPHINE SULFATE (VistaPharm), MORPHINE SULFATE (Zydus Pharmaceuticals (USA)), MORPHINE SULFATE EXTENDED-RELEASE (Sun Pharmaceutical Industries), MORPHINE SULFATE ORAL SOLUTION (Nostrum Laboratories)
組成式   
(C17H19NO3)2. H2SO4. 5H2O
質量    
758.2932
分子量   
758.8302
構造式   
Simcomp   
クラス   
精神神経系用薬
 DG01564  オピオイド受容体作動薬
  DG01563  μ-オピオイド受容体作動薬
鎮痛薬
 DG01984  オピオイド系鎮痛薬
代謝酵素基質薬
 DG02924  UGT基質薬
コード   
薬効分類: 8114
ATCコード: N02AA01
化学構造グループ: DG00810
商品 (DG00810): D00842<JP/US> D02271<JP>
効能    
麻薬性鎮痛薬, オピオイド受容体作動薬
コメント  
あへんアルカロイド
ターゲット 
OPRM1 [HSA:4988] [KO:K04215]
  パスウェイ
hsa04080  神経刺激性リガンドとレセプターの相互作用
代謝    
Enzyme: UGT [KO:K00699]
相互作用  

構造マップ 
map07039  麻薬性鎮痛剤
map07224  オピオイド受容体の作動薬と拮抗薬
他のマップ 
map05032  モルヒネ依存症
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 8  麻薬
  81  アルカロイド系麻薬(天然麻薬)
   811  あへんアルカロイド系麻薬
    8114  モルヒネ系製剤
     D00842  モルヒネ硫酸塩水和物 (JP17)
医療用医薬品のATC分類 [BR:jp08303]
 N 神経系
  N02 鎮痛薬
   N02A オピオイド
    N02AA 天然アヘンアルカロイド
     N02AA01 モルフィン
      D00842  モルヒネ硫酸塩水和物 (JP17) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 鎮痛薬
  オピオイド鎮痛薬, 長時間型
   モルヒネ
    D00842  モルヒネ硫酸塩水和物 (JP17)
  オピオイド鎮痛薬, 短時間型
   モルヒネ
    D00842  モルヒネ硫酸塩水和物 (JP17)
ターゲットに基づく医薬品分類 [BR:jp08310]
 Gタンパク質共役受容体
  ロドプシンファミリー
   オピオイド
    OPRM1
     D00842  モルヒネ硫酸塩水和物 (JP17) <JP/US>
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D00842  モルヒネ硫酸塩水和物
薬物代謝酵素とトランスポーター [jp08309.html]
 薬物代謝酵素
  D00842
リンク   
CAS: 6211-15-0
PubChem: 7847907
ChEBI: 50731
ChEMBL: CHEMBL2103744
DrugBank: DB00295
LigandBox: D00842
日化辞: J244.872F
LinkDB    

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