イリノテカン塩酸塩水和物 (JP17);
塩酸イリノテカン;
Irinotecan hydrochloride (USP);
Irinotecan hydrochloride hydrate (JP17);
Irinotecan hydrochloride trihydrate;
CPT 11;
CPT-11

オニバイド (日本セルヴィエ), カンプト (ヤクルト本社), トポテシン (第一三共)

イリノテカン塩酸塩 (サンファーマ), イリノテカン塩酸塩 (ニプロ), イリノテカン塩酸塩 (ハンルイ医薬), イリノテカン塩酸塩 (ファイザー), イリノテカン塩酸塩 (マイラン製薬), イリノテカン塩酸塩 (大鵬薬品工業), イリノテカン塩酸塩 (日医工ファーマ), イリノテカン塩酸塩 (東和薬品), イリノテカン塩酸塩 (武田テバファーマ), イリノテカン塩酸塩 (沢井製薬)
商品一覧

ONIVYDE (Ipsen Biopharmaceuticals), CAMPTOSAR (Pharmacia and Upjohn Company LLC)

IRINOTECAN HYDROCHLOIDE (BluePoint Laboratories), IRINOTECAN HYDROCHLOIDE (Gland Pharma Limited), IRINOTECAN HYDROCHLOIDE (Xiromed LLC), IRINOTECAN HYDROCHLORIDE (Actavis Pharma), IRINOTECAN HYDROCHLORIDE (Actavis Pharma), IRINOTECAN HYDROCHLORIDE (Apotex Corp.), IRINOTECAN HYDROCHLORIDE (Areva Pharmaceuticals), IRINOTECAN HYDROCHLORIDE (Areva Pharmaceuticals), IRINOTECAN HYDROCHLORIDE (Armas Pharmaceuticals), IRINOTECAN HYDROCHLORIDE (Armas Pharmaceuticals), IRINOTECAN HYDROCHLORIDE (Armas Pharmaceuticals), IRINOTECAN HYDROCHLORIDE (AuroMedics Pharma LLC), IRINOTECAN HYDROCHLORIDE (BluePoint Laboratories), IRINOTECAN HYDROCHLORIDE (BluePoint Laboratories), IRINOTECAN HYDROCHLORIDE (Fresenius Kabi USA), IRINOTECAN HYDROCHLORIDE (Hikma Pharmaceuticals USA), IRINOTECAN HYDROCHLORIDE (Hikma Pharmaceuticals USA), IRINOTECAN HYDROCHLORIDE (Hospira), IRINOTECAN HYDROCHLORIDE (Ingenus Pharmaceuticals), IRINOTECAN HYDROCHLORIDE (Northstar Rx LLC), IRINOTECAN HYDROCHLORIDE (Qilu Pharmaceutical), IRINOTECAN HYDROCHLORIDE (Sagent Pharmaceuticals)

C33H38N4O6. 3H2O. HCl

676.2875

677.1848

抗悪性腫瘍薬, トポイソメラーゼI阻害薬

小細胞肺癌 [DS:H00013]
非小細胞肺癌 [DS:H00014]
子宮頸癌 [DS:H00030]
卵巣癌 [DS:H00027]
胃癌 [DS:H00018]
結腸・直腸癌 [DS:H00020]
乳癌 [DS:H00031]
有棘細胞癌 [DS:H00040]
悪性リンパ腫, 非ホジキンリンパ腫 [DS:H02418]
小児悪性固形腫瘍 [DS:H02421]
膵癌 [DS:H00019]

カンプトテシン系
細胞周期S期に特異的に作用
プロドラッグ活性体: SN-38 [CPD:C11173]

TOP1 [HSA:7150] [KO:K03163]

Enzyme: CES [HSA:1066 221223 23491 8824]; CYP3A4 [HSA:1576], UGT1A1 [HSA:54658]

DDI search