KEGG   DRUG: エスゾピクロンHelp
エントリ  
D02624                      Drug                                   

一般名   
エスゾピクロン (JAN);
Eszopiclone (JAN/USAN/INN)
商品名   
米国の商品 
  後発品
ESZOPICLONE (A-S Medication Solutions), ESZOPICLONE (A-S Medication Solutions), ESZOPICLONE (A-S Medication Solutions), ESZOPICLONE (A-S Medication Solutions), ESZOPICLONE (A-S Medication Solutions), ESZOPICLONE (A-S Medication Solutions), ESZOPICLONE (A-S Medication Solutions), ESZOPICLONE (Aidarex Pharmaceuticals LLC), ESZOPICLONE (Aidarex Pharmaceuticals LLC), ESZOPICLONE (Aidarex Pharmaceuticals LLC), ESZOPICLONE (Aphena Pharma Solutions - Tennessee), ESZOPICLONE (Aphena Pharma Solutions - Tennessee), ESZOPICLONE (Aurobindo Pharma Limited), ESZOPICLONE (Bryant Ranch Prepack), ESZOPICLONE (Bryant Ranch Prepack), ESZOPICLONE (Bryant Ranch Prepack), ESZOPICLONE (DIRECT RX), ESZOPICLONE (DIRECT RX), ESZOPICLONE (Direct_Rx), ESZOPICLONE (Dr. Reddy's Laboratories Limited), ESZOPICLONE (Glenmark Pharmaceuticals Inc. USA), ESZOPICLONE (Golden State Medical Supply), ESZOPICLONE (Lake Erie Medical DBA Quality Care Products LLC), ESZOPICLONE (Lake Erie Medical DBA Quality Care Products LLC), ESZOPICLONE (Lake Erie Medical DBA Quality Care Products LLC), ESZOPICLONE (Lupin Pharmaceuticals), ESZOPICLONE (Macleods Pharmaceuticals Limited), ESZOPICLONE (Mylan Institutional), ESZOPICLONE (Mylan Pharmaceuticals), ESZOPICLONE (NuCare Pharmaceuticals), ESZOPICLONE (NuCarePharmaceuticals), ESZOPICLONE (OrchidPharma), ESZOPICLONE (PD-Rx Pharmaceuticals), ESZOPICLONE (Preferred Pharmaceuticals), ESZOPICLONE (Preferred Pharmaceuticals), ESZOPICLONE (Preferred Pharmaceuticals), ESZOPICLONE (Preferred Pharmaceuticals), ESZOPICLONE (Proficient Rx LP), ESZOPICLONE (Proficient Rx LP), ESZOPICLONE (Proficient Rx LP), ESZOPICLONE (Proficient Rx LP), ESZOPICLONE (Proficient Rx LP), ESZOPICLONE (Proficient Rx LP), ESZOPICLONE (Proficient Rx LP), ESZOPICLONE (Proficient Rx LP), ESZOPICLONE (REMEDYREPACK), ESZOPICLONE (REMEDYREPACK), ESZOPICLONE (REMEDYREPACK), ESZOPICLONE (REMEDYREPACK), ESZOPICLONE (St. Mary's Medical Park Pharmacy), ESZOPICLONE (St. Mary's Medical Park Pharmacy), ESZOPICLONE (Sun Pharmaceutical Industries), ESZOPICLONE (Teva Pharmaceuticals USA), ESZOPICLONE (Unit Dose Services), ESZOPICLONE (Unit Dose Services), ESZOPICLONE (Unit Dose Services), ESZOPICLONE (Unit Dose Services), ESZOPICLONE (Unit Dose Services), ESZOPICLONE (West-Ward Pharmaceuticals Corp.)
組成式   
C17H17ClN6O3
質量    
388.1051
分子量   
388.8083
構造式   
Mol fileKCF fileDB search
Simcomp    SIMCOMP
クラス   
精神神経系用薬
 DG01836  非ベンゾジアゼピン系催眠鎮静薬
 DG01567  GABA-A受容体作動薬
代謝酵素基質薬
 DG02855  CYP2E1基質薬
 DG02913  CYP3A4基質薬
コード   
薬効分類: 1129
ATCコード: N05CF04
商品: D02624<JP/US>
効能    
催眠鎮静薬
  疾患
不眠症 [DS:H01609]
ターゲット 
  パスウェイ
hsa04080  神経刺激性リガンドとレセプターの相互作用
hsa04727  GABA作動性シナプス
代謝    
Enzyme: CYP3A4 [HSA:1576]; CYP2E1 [HSA:1571]
相互作用  
Drug interaction
構造マップ 
map07032  催眠薬
map07230  GABA-A受容体の作動薬と拮抗薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 1  神経系及び感覚器官用医薬品
  11  中枢神経系用薬
   112  催眠鎮静剤、抗不安剤
    1129  その他の催眠鎮静剤、抗不安剤
     D02624  エスゾピクロン (JAN)
医療用医薬品のATC分類 [BR:jp08303]
 N 神経系
  N05 精神抑制薬
   N05C 睡眠薬と鎮静薬
    N05CF ベンゾジアゼピン関連薬物
     N05CF04 エスゾピクロン
      D02624  エスゾピクロン (JAN) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 睡眠障害治療薬
  GABA受容体修飾薬
   エスゾピクロン
    D02624  エスゾピクロン (JAN)
ターゲットに基づく医薬品分類 [BR:jp08310]
 イオンチャネル
  リガンド依存性イオンチャネル
   GABA (イオンチャネル型)
    GABR
     D02624  エスゾピクロン (JAN) <JP/US>
日本の新薬 [jp08318.html]
 新有効成分含有医薬品
  D02624
日本・米国・欧州の新薬 [jp08328.html]
 日米欧での承認状況
  D02624
BRITE hierarchy
リンク   
CAS: 138729-47-2
PubChem: 17396794
ChEBI: 53760
ChEMBL: CHEMBL1522
DrugBank: DB00402
LigandBox: D02624
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