Danio rerio (zebrafish): 556286 Help Entry 556286            CDS       T01004                                  Gene name sos1 Definition (RefSeq) son of sevenless homolog 1   KO K03099   son of sevenless Organism dre  Danio rerio (zebrafish) Pathway dre04010   MAPK signaling pathway dre04012   ErbB signaling pathway dre04068   FoxO signaling pathway dre04150   mTOR signaling pathway dre04510   Focal adhesion dre04540   Gap junction dre04810   Regulation of actin cytoskeleton dre04910   Insulin signaling pathway dre04912   GnRH signaling pathway Brite KEGG Orthology (KO) [BR:dre00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     556286 (sos1)    04012 ErbB signaling pathway     556286 (sos1)    04068 FoxO signaling pathway     556286 (sos1)    04150 mTOR signaling pathway     556286 (sos1)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     556286 (sos1)    04540 Gap junction     556286 (sos1)   09142 Cell motility    04810 Regulation of actin cytoskeleton     556286 (sos1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     556286 (sos1)    04912 GnRH signaling pathway     556286 (sos1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04990 Domain-containing proteins not elsewhere classified [BR:dre04990]     556286 (sos1) Domain-containing proteins not elsewhere classified [BR:dre04990]  Pleckstrin homology (PH) domain-containing proteins   Dbl-Like RhoGEF family proteins    556286 (sos1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RasGEF Histone Motif Other DBs NCBI-GeneID:  556286 NCBI-ProteinID:  NP_001076462 ZFIN:  ZDB-GENE-070209-128 Ensembl:  ENSDARG00000100503 Vega:  OTTDARG00000043150 UniProt:  A2RRV5 LinkDB All DBs Position 11 AA seq 713 aa AA seqDB search MQAPPFQYDFYSEENAHKWRGLLVPSLNKVLNQVHPKLSSQQEALQYIEGLILVLLNTLC QAQPRTVQDVEERVQRSFPHPIEKWAIADAQAAIEKRKRRNPLALPVDKIHPLLKEVLGY KIDHQVSVYIVAVLEYISADILKLAGNYVRNIRHYEISQQDITVAMCADKVLMDMLHPIE IARQLTLLESDFYRAVQPSELVGSVWTKEDKEINSPNLLRMIRHTTNLTLWLEKCIVETE NVEERVSVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQRKILEE AHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPDFLKRHGTELINFSKRRK VAEITGEIQQYQNQPYCLRVENDIRKFFENLNPMEDMMEKEFTDYLFNKSLEIEPRNART LPRFAKKYSCPLKSPGVRPSAVRPGAMRHPTPLQNEPRKISYSRIPDSETESSAASAPNS PRTPLTPPPASAASTDTCSVFDSPQQPSSPFHSNSECVFAPVALPHGPRSSSVSSMMGFL RNDDPPVPPPVPPRRRPESAPAESSPSKMMSTHLDSPPAIPPRQPTSSKVYSPRYSLTDP PESPPLLPPREPVRTPDVFCSSPLHLQPPPPGRRAPELQAFFPPQTPSPSPLGPRKHPEP PPEPPLGPPVPPRLSTAGPPAHIPKLPPKTYKRESVHREGPPPPLLLENANPT NT seq 2142 nt NT seq  +upstreamnt  +downstreamnt atgcaggctccgccctttcagtatgacttctacagtgaggagaacgcgcacaagtggaga ggcctgctggtgccgtcactcaacaaggtgcttaatcaggtgcacccgaagctgtcgtcc cagcaggaggcgctgcagtacatcgaggggctgatcttggtgctgctcaacacactctgc caggcacagcctcgcactgtacaggatgtggaggagcgtgtgcagaggagttttccacac ccgatagagaaatgggcgatcgcagatgctcaggccgccatcgagaagaggaagaggagg aacccgctggcgctgcccgtggacaagatacatccactgctcaaggaggttctgggctat aagatcgaccaccaggtgtcggtgtacatcgtggcggtgctggagtacatctctgcagac atactgaagctggctggaaactacgtcagaaacatccggcactatgagatctcacagcag gacatcactgtggccatgtgtgctgataaggtgctgatggacatgctccaccccatcgag atcgcccgccagctcacactgctggagtctgacttctacagggcggtgcagccgtcagag ctggtgggaagcgtctggactaaagaagataaagagatcaactctccaaacctgctgagg atgatcagacacaccaccaacctcacactctggctggagaagtgtatagtggagacggag aatgtggaggagcgtgtgtccgtggtgtcgcgtatcattgagatcctgcaggtctttcag gagctcaacaacttcaatggtgtgctggaggtggtgagcgccatgaactcctcacccgtc tacaggctcgaccacaccttcgagcaaatccccagcagacagaggaagatcctggaggaa gctcatgagctcagtgaagatcattataagaagtatctggccaagctcaggtccatcaac ccaccctgtgtgcccttctttggcatttatttaacgaacatcttgaagacggaggaggga aacccagacttcctgaagcgccacggcactgagctgatcaacttcagcaagaggaggaaa gtggctgagattactggagagatccagcagtaccagaaccagccctactgtctgcgggtg gagaacgacatccggaagttcttcgagaacctaaacccgatggaggacatgatggagaag gagttcacagattacctgttcaacaaatctctggagatcgagccgcgcaatgcacgcaca ctgcccagattcgccaagaagtacagctgtcctctgaagtctccgggggtccgtccgtcc gcggtgcggccgggagcgatgcgacacccgacgccgctgcagaacgagccgcgcaagatc agctacagccgcatccctgacagcgagacggagagcagcgcagcgtctgcaccaaactcc cccagaacacccctgacacccccacccgcatccgctgcatccactgacacctgcagtgtg ttcgactctccacagcagccctccagcccgttccactccaacagcgagtgtgtgttcgct ccggtggctctgccgcacggcccacgatcctcttcagtgtcctctatgatgggttttctg aggaatgatgatcctccagttcctcctcctgtcccgccgcgccgccggcccgagtctgcc cccgccgagtcctcgccctccaagatgatgtcaacacacctggacagtcctcctgcgatt ccccctcgtcagccgaccagcagtaaggtgtattctcctcgatactcgctgacggatcct ccggagagcccacctctgctgccgccgcgggagccggtgcggaccccggacgtgttctgc agctcgccgttacacctgcagccgccgccgccgggccgccgcgcccccgagctgcaggcc ttcttcccaccacagacgccctcaccgtcaccgctggggccgcggaaacacccggagccg ccgccggagcccccactggggccgcccgtccccccacgcctcagcaccgccggcccgccc gcacacatccccaaactgcccccaaaaacatacaagagggagtcagtgcaccgcgagggt ccgccgccgccactgctgctggagaacgccaaccccacatga

Danio rerio (zebrafish): 561670 Help Entry 561670            CDS       T01004                                  Gene name sos2 Definition (RefSeq) son of sevenless homolog 2   KO K03099   son of sevenless Organism dre  Danio rerio (zebrafish) Pathway dre04010   MAPK signaling pathway dre04012   ErbB signaling pathway dre04068   FoxO signaling pathway dre04150   mTOR signaling pathway dre04510   Focal adhesion dre04540   Gap junction dre04810   Regulation of actin cytoskeleton dre04910   Insulin signaling pathway dre04912   GnRH signaling pathway Brite KEGG Orthology (KO) [BR:dre00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     561670 (sos2)    04012 ErbB signaling pathway     561670 (sos2)    04068 FoxO signaling pathway     561670 (sos2)    04150 mTOR signaling pathway     561670 (sos2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     561670 (sos2)    04540 Gap junction     561670 (sos2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     561670 (sos2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     561670 (sos2)    04912 GnRH signaling pathway     561670 (sos2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04990 Domain-containing proteins not elsewhere classified [BR:dre04990]     561670 (sos2) Domain-containing proteins not elsewhere classified [BR:dre04990]  Pleckstrin homology (PH) domain-containing proteins   Dbl-Like RhoGEF family proteins    561670 (sos2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RasGEF RasGEF_N RhoGEF Histone PH Motif Other DBs NCBI-GeneID:  561670 NCBI-ProteinID:  NP_001334612 ZFIN:  ZDB-GENE-090319-5 Ensembl:  ENSDARG00000060506 Vega:  OTTDARG00000029600 UniProt:  F1R019 LinkDB All DBs Position 13 AA seq 1341 aa AA seqDB search MQHDFSSSEENSARWRGLFVQGLRKVQVQVHPNLSAKEDALQHIEALILQLLNKLCVTQP RTIADVEDRVQKTFPNPIDKWAMGDAQNAIEKRKRRNPLLLPVDKIHPLLKEVLGYKIDY NVCLYIVAVLEYISADILKLAGNYVSNIRHYEISQQDITVSMCADKVLMDMFDQEEEMGL LSQSVEEVSSSGVLTYDDLVRLEIAEERQYLRELDLIIKVFRQAFMSNSKLFSAQDVELA FSNILEVQELTVKLLGLIEDAVEMTADGSPHPLVGSCFEDLAEEQAFDPYETLSQDILSK EFCQHFNTLMSRPTVALHFQSIAEGFKEAVQYVLPQLMMVPVYHCIHYFELLQQLQECSE EQDDRECLKQAQTALINLQCSIERIYAKHQPRRKQGEPLYRLYSRASRSKQAAIKRMNDI QKSIDGWEGKDIGQCCSQFILEGALLRAGAKHERHNFLFDGLMISCKANQSSRLPGAGSG AEFRLKEKFVLRKYRIVDREDSPEFRHAFELVGREESGAVFSARSAEEKSAWMAALVTLQ YRPTLDRMLDTVLHREEQAQPLRLPSPDVYRFAIQDSEENIVFEEGAQSKTGIPIIKAGT VVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQDLLTLLIERIEIPEPEPSEADREALWN GEQPMAAELQRFRREYVQPVQLRVLNVFRQWVEHHFYDFENDPELYERLEGYLISTTQLR GKSMRKWVESISKIMRRKIQMQSNGISHNITFESPPPPIEWHISRPGQVDTFDLMTLHPI EIARQLTLLESDLYRAVRPSELVGSVWTKEDKEKNSPNLLRMIRHTTNLTLWFEKCIVEA ENVDERVAVFSRIIEILQVFQELNNFNGVLEIVSAINSVPVYRLDHTFEAVPERKRRILE EAVELSQDHFKKYLAKLKSINPPCVPFFGIYLTNILKTEEGNPDFLKRDGKELINFSKRR KVAEITGEIQQYQNQPYCLKVEHDIKRFFENLNPMGNMNEKDFSDYLFNKSLEIEPRNSK QPPRFPRKTTYSLKSPGVRPVRQAVGGGGTLKGHPVPLEREPPHKITFRSIAETEPETPP SLPTSPNTPTPPQSASSDFNSVFEQDFMPYGNNTIFAPVFLPQSKFQSVSCGSLHQLMSD EPLKPPPLPPRRKDTSSDKNSRSDSPPAIPPRLPPPPRLQPRVPVINGPTDGPLPSPPPP LPRDPLPDTPPPVPQRPPEIFINYPVNMQPSPGGRFHWDFTTSPSTPNTPPGTPSPRAVL PGTPSPRVPRRPCTPSVSQPILVHLPPPTPAPPIPPRHNSTSALPKLPPKTYKRELSQSS HTLSQPSLHTLSLVDNRDSNE NT seq 4026 nt NT seq  +upstreamnt  +downstreamnt atgcagcacgacttcagctccagcgaggagaacagcgcgagatggcgaggcctgttcgtg caggggctgcgaaaggtgcaggtgcaagtgcatccaaacctgtcggctaaagaagatgca ctccagcacattgaggcacttatactgcagctcctgaacaagctgtgtgttacacagccc agaacaatagctgatgtagaggaccgcgtccagaagacgttcccaaatcccatcgataaa tgggccatgggtgacgctcagaatgcaatagagaaacgcaagcgaagaaacccgctgctg ctgccagttgataagatacatccactactgaaggaggtgctgggctataagatcgactat aatgtgtgtctatatattgttgctgtgctggagtacatctcagctgacatcctcaagctg gctggaaactacgtgagcaacattcgacattatgagatcagccagcaggacatcactgtc tccatgtgtgctgataaggtgttaatggatatgttcgatcaagaagaggagatggggctg ttgtctcagagtgtggaggaggtgtcttcatctggtgtgctcacatatgatgacctggtg cgtctggagatcgcggaggagcgtcagtatctgcgggagctcgatctcatcatcaaagta ttccgccaagcctttatgtccaatagcaaactcttctccgctcaggatgtggagctggcg ttcagtaatattctagaggttcaggagttaacagtgaaactgttgggtcttattgaggat gcggtagaaatgacagctgacgggagtccacaccctcttgtgggcagctgctttgaagac ctcgctgaagagcaggcatttgatccctatgagacgctctctcaggacatcctctctaaa gaattctgtcaacatttcaacacactgatgtcccgccccactgtagctctgcacttccag tcaattgcagaaggctttaaggaggcagtgcagtacgtgcttcctcagttgatgatggtt ccagtttaccactgcattcactattttgaactgttacagcaattgcaggagtgcagtgaa gagcaagatgacagagagtgtttgaaacaggcacagactgcactgatcaacctacaatgc agcattgaacgcatatatgctaagcaccaaccacggcgcaaacaaggggaaccactgtat cgattgtatagtcgtgcatctcgtagcaagcaggcggctataaagcgtatgaacgacatc cagaagagtattgatggctgggagggcaaagacattggtcagtgttgtagccagttcatc ctggagggggcactccttcgggctggtgccaaacatgagcggcacaactttctattcgat ggcctcatgataagctgcaaagccaatcagagctccaggttgccaggagcaggcagtggg gcagagtttcgtctgaaagagaagttcgtgttacgcaaatatcgcattgtagatcgcgag gattcaccagagttccgtcatgcatttgagctggtgggccgtgaggaaagcggagcagtg tttagtgcccgttcagcagaagaaaagagtgcatggatggctgcgctggtcactctgcag taccggcccacactggaccgcatgctggacactgtcctgcaccgtgaagaacaagcacaa ccactgaggctgccatcaccagacgtctaccggttcgccatccaggactccgaagagaat atcgtgttcgaggaaggagcacaaagcaagactggaatccccattattaaagctgggaca gtggtcaagctcattgagagactgacgtaccacatgtacgcagacccaaattttgtgcgt acgtttctgactacataccgctctttctgcaaaccacaagacctgctcacactactgatt gaaaggattgagattccagagcccgaaccatcagaagcagatcgagaagctctctggaat ggagaacaaccaatggcagctgagcttcagagatttcgcagagaatacgtgcagcccgtc caactcagggtcttgaatgtgttccgtcagtgggtggaacatcacttttatgactttgag aatgatcctgaactctacgagagacttgaaggatatcttatcagcaccacacagcttaga ggtaaatctatgcgtaagtgggtggagtctatcagtaagatcatgagacggaagatacaa atgcagtctaacggcattagtcacaacattacctttgagagcccacctccacccatcgaa tggcacatcagtcgccctgggcaggtcgacacctttgacctcatgacccttcatccgata gaaattgctcgccagttaacacttctggagtctgatctgtacagagctgttcgtccgtct gagctcgtaggaagtgtttggacaaaggaagataaagagaagaactctcccaatctgctg aggatgatcagacacacaaccaatctcacactgtggtttgaaaagtgtatagtagaggct gaaaatgtagacgagagggttgctgtattttctcgcattattgagatcctgcaggtgttt caagagcttaataactttaatggggttttggagattgtgagcgccatcaattctgtaccg gtgtatcgtctggaccacacatttgaggcagtgcctgagaggaagaggaggattctagaa gaagctgttgaactcagtcaggatcattttaagaaatatctcgccaaactcaagtccatc aacccaccctgtgtacctttctttggtatctacctgactaacattctgaagactgaagag gggaatccagatttcctaaagcgggacggaaaagaactgatcaacttcagcaagagacgc aaagtagcagaaatcactggagaaatccagcagtaccagaaccaaccctactgcctcaaa gtggaacacgacataaagaggttttttgagaatctgaatccaatggggaatatgaatgaa aaggatttctctgactatttgttcaataagtctttagaaatcgaaccacggaacagcaag cagccacctagatttcccagaaagactacatattctctgaagtctccgggcgttcggcct gtgcgccaggcggtaggtggaggagggacgctaaaaggtcacccagtgccattagaaaga gaaccacctcacaaaatcaccttcaggagcatcgcagaaactgaacccgagacgcctccc tctctgcccacctctccaaacacacccacccctccgcagtccgccagctctgacttcaac tctgtgtttgagcaggacttcatgccctacggtaacaacaccatatttgccccagttttt ctgccgcagtccaagttccagtctgtgtcatgtggtagtttacaccagttgatgagtgat gagccactcaagccccctccattacctcctcgcaggaaagatacttcttcagataagaat tccaggtctgacagtcctcctgccattccaccacgattgcctcctcctccccgcctgcag ccgcgtgtcccagtgatcaacgggccgacggatgggcccttgccgagccccccaccacct ctgccccgtgacccccttccggacactcctccaccagtgccccagagaccacccgagatc ttcatcaactacccagtgaacatgcagccatctccagggggccgtttccactgggacttc accacctcacctagcactcctaataccccgcctggcaccccctctccccgtgctgtcctc cctggaaccccttctccacgtgtgccccggcgcccctgcacacccagcgtcagtcaaccc atactggttcaccttcctcccccgacaccggcacctcccatcccgcctcggcacaactcc acctccgccctgccaaaactgccacccaagacttacaaaagagaactgtctcaatcttca cacactctttctcagccctccctacacacactctcgctagttgacaacagggacagcaac gaataa

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