KEGG   Desmodus rotundus (common vampire bat): 112304528
Entry
112304528         CDS       T05907                                 

Gene name
TGFBR1
Definition
(RefSeq) TGF-beta receptor type-1
  KO
K04674  TGF-beta receptor type-1 [EC:2.7.11.30]
Organism
dro  Desmodus rotundus (common vampire bat)
Pathway
dro04010  MAPK signaling pathway
dro04060  Cytokine-cytokine receptor interaction
dro04068  FoxO signaling pathway
dro04144  Endocytosis
dro04218  Cellular senescence
dro04350  TGF-beta signaling pathway
dro04371  Apelin signaling pathway
dro04380  Osteoclast differentiation
dro04390  Hippo signaling pathway
dro04520  Adherens junction
dro04659  Th17 cell differentiation
dro04926  Relaxin signaling pathway
dro04933  AGE-RAGE signaling pathway in diabetic complications
dro05142  Chagas disease
dro05161  Hepatitis B
dro05166  Human T-cell leukemia virus 1 infection
dro05200  Pathways in cancer
dro05210  Colorectal cancer
dro05212  Pancreatic cancer
dro05220  Chronic myeloid leukemia
dro05225  Hepatocellular carcinoma
dro05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:dro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    112304528 (TGFBR1)
   04350 TGF-beta signaling pathway
    112304528 (TGFBR1)
   04390 Hippo signaling pathway
    112304528 (TGFBR1)
   04371 Apelin signaling pathway
    112304528 (TGFBR1)
   04068 FoxO signaling pathway
    112304528 (TGFBR1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    112304528 (TGFBR1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    112304528 (TGFBR1)
  09143 Cell growth and death
   04218 Cellular senescence
    112304528 (TGFBR1)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    112304528 (TGFBR1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    112304528 (TGFBR1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    112304528 (TGFBR1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    112304528 (TGFBR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112304528 (TGFBR1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    112304528 (TGFBR1)
   05212 Pancreatic cancer
    112304528 (TGFBR1)
   05225 Hepatocellular carcinoma
    112304528 (TGFBR1)
   05226 Gastric cancer
    112304528 (TGFBR1)
   05220 Chronic myeloid leukemia
    112304528 (TGFBR1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    112304528 (TGFBR1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    112304528 (TGFBR1)
   05161 Hepatitis B
    112304528 (TGFBR1)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    112304528 (TGFBR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dro01001]
    112304528 (TGFBR1)
Enzymes [BR:dro01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     112304528 (TGFBR1)
Protein kinases [BR:dro01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR1 family [OT]
   112304528 (TGFBR1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr TGF_beta_GS Pkinase_fungal APH FTA2 Activin_recp
Other DBs
NCBI-GeneID: 112304528
NCBI-ProteinID: XP_024415933
LinkDB
Position
Unknown
AA seq 434 aa
MCIAEIDLIPRDRPFVCAPSTKTGSVTTPYCCNQDHCNKIELPTTGKPSPGLGPVELAAV
IAGPVCFVCISLMLMVYVCHNRAAIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMTTSGS
GSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIY
QTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALST
ASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAP
NHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYY
DLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIK
KTLSQLSQQEGIKM
NT seq 1305 nt   +upstreamnt  +downstreamnt
atgtgcatagctgaaattgacttaattcctcgagacaggccgttcgtgtgcgcaccgtcc
acgaaaaccgggtccgtcacgacgccgtactgctgcaatcaggaccactgcaacaagata
gaactccccaccacgggaaagccgtccccaggcctcggtcccgttgaactggcagctgtc
attgccgggccagtctgctttgtctgcatctccctcatgttgatggtctatgtctgccat
aaccgcgctgccattcaccatcgagtgccgaacgaagaggacccttccttggatcgccct
tttatttcagagggcactacgctgaaagatttgatttatgatatgacgacatcggggtct
ggatcaggtttaccattgcttgtccagagaacaattgcgagaactatcgtattacaagaa
agtattggcaaaggtcgatttggagaagtttggcgaggaaagtggagaggagaagaagtc
gctgttaaaatattctcctccagagaagaacggtcctggttccgtgaggccgagatttat
cagaccgtgatgttacgccatgagaacatcttgggatttatagcagcagacaataaagac
aatgggacgtggactcagctctggttggtatcagattatcacgagcatggatccctcttt
gattatttgaacagatacacggttactgtggaaggaatgataaaactcgctctgtccaca
gcaagtggacttgctcaccttcatatggagattgtcggcacccaaggaaaaccagccatt
gctcacagagatttgaaatcaaaaaacatcttggtaaaaaagaacggaacttgctgtatt
gcagacttggggctggcagtaaggcacgattcagccacagacacgattgatatcgcccca
aaccacagagtgggaacaaaaaggtacatggcccccgaagtcctagatgattccataaat
atgaaacactttgaatccttcaagcgcgccgacatctatgcaatgggcttagtgttctgg
gaaatagcccgaagatgttccattggtggaattcacgaagattaccagctgccttattac
gatcttgtaccctctgatccatccgttgaagaaatgagaaaggtggtttgtgaacagaag
ttgaggccaaatatcccaaacagatggcagagctgtgaagccttgagagtaatggccaaa
attatgagagaatgttggtacgccaacggagcagctcggctcacagctttgcggattaag
aaaactttgtcgcaactcagtcaacaggaaggcatcaaaatgtaa

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