Desmodus rotundus (common vampire bat): 112306912 Help Entry 112306912         CDS       T05907                                  Gene name EGFR Definition (RefSeq) epidermal growth factor receptor   KO K04361   epidermal growth factor receptor [EC:2.7.10.1] Organism dro  Desmodus rotundus (common vampire bat) Pathway dro01521   EGFR tyrosine kinase inhibitor resistance dro01522   Endocrine resistance dro04010   MAPK signaling pathway dro04012   ErbB signaling pathway dro04014   Ras signaling pathway dro04015   Rap1 signaling pathway dro04020   Calcium signaling pathway dro04066   HIF-1 signaling pathway dro04068   FoxO signaling pathway dro04072   Phospholipase D signaling pathway dro04144   Endocytosis dro04151   PI3K-Akt signaling pathway dro04510   Focal adhesion dro04520   Adherens junction dro04540   Gap junction dro04630   JAK-STAT signaling pathway dro04810   Regulation of actin cytoskeleton dro04912   GnRH signaling pathway dro04915   Estrogen signaling pathway dro04921   Oxytocin signaling pathway dro04926   Relaxin signaling pathway dro04928   Parathyroid hormone synthesis, secretion and action dro04934   Cushing syndrome dro05160   Hepatitis C dro05163   Human cytomegalovirus infection dro05165   Human papillomavirus infection dro05171   Coronavirus disease - COVID-19 dro05200   Pathways in cancer dro05205   Proteoglycans in cancer dro05206   MicroRNAs in cancer dro05210   Colorectal cancer dro05212   Pancreatic cancer dro05213   Endometrial cancer dro05214   Glioma dro05215   Prostate cancer dro05218   Melanoma dro05219   Bladder cancer dro05223   Non-small cell lung cancer dro05224   Breast cancer dro05225   Hepatocellular carcinoma dro05226   Gastric cancer dro05230   Central carbon metabolism in cancer dro05231   Choline metabolism in cancer dro05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:dro00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     112306912 (EGFR)    04012 ErbB signaling pathway     112306912 (EGFR)    04014 Ras signaling pathway     112306912 (EGFR)    04015 Rap1 signaling pathway     112306912 (EGFR)    04630 JAK-STAT signaling pathway     112306912 (EGFR)    04066 HIF-1 signaling pathway     112306912 (EGFR)    04068 FoxO signaling pathway     112306912 (EGFR)    04020 Calcium signaling pathway     112306912 (EGFR)    04072 Phospholipase D signaling pathway     112306912 (EGFR)    04151 PI3K-Akt signaling pathway     112306912 (EGFR)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     112306912 (EGFR)   09144 Cellular community - eukaryotes    04510 Focal adhesion     112306912 (EGFR)    04520 Adherens junction     112306912 (EGFR)    04540 Gap junction     112306912 (EGFR)   09142 Cell motility    04810 Regulation of actin cytoskeleton     112306912 (EGFR)  09150 Organismal Systems   09152 Endocrine system    04912 GnRH signaling pathway     112306912 (EGFR)    04915 Estrogen signaling pathway     112306912 (EGFR)    04921 Oxytocin signaling pathway     112306912 (EGFR)    04926 Relaxin signaling pathway     112306912 (EGFR)    04928 Parathyroid hormone synthesis, secretion and action     112306912 (EGFR)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112306912 (EGFR)    05206 MicroRNAs in cancer     112306912 (EGFR)    05205 Proteoglycans in cancer     112306912 (EGFR)    05230 Central carbon metabolism in cancer     112306912 (EGFR)    05231 Choline metabolism in cancer     112306912 (EGFR)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     112306912 (EGFR)   09162 Cancer: specific types    05210 Colorectal cancer     112306912 (EGFR)    05212 Pancreatic cancer     112306912 (EGFR)    05225 Hepatocellular carcinoma     112306912 (EGFR)    05226 Gastric cancer     112306912 (EGFR)    05214 Glioma     112306912 (EGFR)    05218 Melanoma     112306912 (EGFR)    05219 Bladder cancer     112306912 (EGFR)    05215 Prostate cancer     112306912 (EGFR)    05213 Endometrial cancer     112306912 (EGFR)    05224 Breast cancer     112306912 (EGFR)    05223 Non-small cell lung cancer     112306912 (EGFR)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     112306912 (EGFR)   09172 Infectious disease: viral    05160 Hepatitis C     112306912 (EGFR)    05171 Coronavirus disease - COVID-19     112306912 (EGFR)    05163 Human cytomegalovirus infection     112306912 (EGFR)    05165 Human papillomavirus infection     112306912 (EGFR)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     112306912 (EGFR)    01522 Endocrine resistance     112306912 (EGFR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:dro01001]     112306912 (EGFR)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:dro04147]     112306912 (EGFR) Enzymes [BR:dro01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      112306912 (EGFR) Protein kinases [BR:dro01001]  Receptor tyrosine kinases (RTK)   EGFR family [OT]    112306912 (EGFR) Exosome [BR:dro04147]  Exosomal proteins   Exosomal proteins of colorectal cancer cells    112306912 (EGFR)   Exosomal proteins of pancreatic cancer cells    112306912 (EGFR)   Exosomal proteins of bladder cancer cells    112306912 (EGFR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr GF_recep_IV Pkinase Recep_L_domain Furin-like APH Kinase-like Kdo Motif Other DBs NCBI-GeneID:  112306912 NCBI-ProteinID:  XP_024418711 LinkDB All DBs Position Unknown AA seq 941 aa AA seqDB search MLYNPTTYQVDVNPDGKYSFGATCVKKCPRNYVVTDHGSCVRACGSDSYEVEEDGVRKCK KCEGPCRKVCNGIGIGEFKDTLSINATNIKHFRNCTSISGDLHILPVAFKGDTFTHTQPL DPKELDILKTVKEITGSLLIQAWPENRTDLHAFENLEIIRGRTKQHGRFSFAVVGLNITS LGLRSLKEISDGDVVITGNRHLCYADTVNWKKLFGTSGQKTKVEKNKDRKDCRAQGHVCN PLCSSEGCWGPGPRDCMSCRNVSRDKECVEKCNILEGEPREFEEKSECIRCHPECLPQPM NVTCTGHGPDKCVQCAHYIDGPHCVSTCPEGVMGENSTLVWKFADAQHVCHLCHPNCTYG CAGPGLEGCARGPKIPSIATGIVGGLLLVVVVALGIGLFLRRRHIVRKRTLRRLLQEREL VEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELR EATSPKANKEILDEAYVMASVDHPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDN IGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKE YHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISTVLE KGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIHEFSKMARDPQRYLVIQGDERMH LPSPTDSNFYRALMDEEDMEDVVDADEYLIPQQAFFHSPSTSRTPLLSSLSATSNSSTVA CADRNGQSCPLKEDSFLQRYSSDPTGALTEDVINGTFLPAPEYINQLVPKRPAGSVQNPV YHNQPLNLAPGRDPHYQNPHSNAVGNPEYLNTTPPPTVNGVPDGPTLWVQKGSHQISLDN PDYQQDFFPREAKSNGIFKGPTAENADYLRVGAPSSEFIGA NT seq 2826 nt NT seq  +upstreamnt  +downstreamnt atgctgtacaaccccaccacgtaccaggtggacgtcaacccagatggaaaatacagcttt ggagccacctgtgtgaagaaatgtccccgcaactacgtggtgaccgaccacgggtcgtgt gtccgggcctgcggctcagacagctacgaggtggaggaagacggcgtccgcaagtgtaaa aagtgtgaagggccctgtcgcaaagtctgcaatgggataggaatcggagagttcaaggac accctctccatcaacgccacgaacatcaaacacttccggaactgcacgtccatcagcggg gacctccacatcctgccggtcgctttcaagggggacaccttcacacacacgcaacctctg gaccccaaggagctggacattctcaagaccgtaaaggagatcacagggtctctgctgatt caggcctggccggaaaacaggacggacctccacgcattcgagaacctagagatcatacgc ggcaggacgaagcagcacggccggttttctttcgcggtggtcgggctgaacatcacgtca ctgggactgcgctcgctgaaggagatcagcgacggcgatgtggtcatcacaggaaaccgc cacctgtgctacgcagacacagtgaactggaaaaagctctttgggacctcgggtcagaaa acaaaggttgagaaaaacaaagacagaaaagactgccgggcccaaggccacgtctgcaac ccgctgtgctcatctgaggggtgctggggcccggggccccgggactgcatgtcttgccga aacgtcagccgagacaaggagtgcgtggagaaatgcaacattctcgagggcgagcccagg gagttcgaggagaaatccgagtgcatacggtgccatccggagtgcctgccgcagcccatg aacgtgacctgcacgggacacggaccggacaagtgcgtgcagtgtgcccactacatcgac ggccctcactgtgtcagcacctgcccagagggggtcatgggcgaaaacagcacgctggtc tggaagttcgcggacgcccagcacgtctgtcacctgtgccatccaaactgtacctacggc tgtgcggggccgggccttgaaggctgcgcaagggggcccaagatcccgtccatcgccacg gggattgtgggcggcctcctcttggtggtggtggtggccctcgggataggcctgtttctg cgcaggcgccacatcgtccggaagcgcacgctgcggaggctgctgcaggagcgggagctc gtggagccccttacacccagcggagaagcacccaaccaagctctcctgcggatcttaaag gagacagaattcaaaaaaatcaaggtgctgggctccggcgcgtttggcaccgtgtacaag gggctctggatccccgagggcgagaaggtcaaaatccccgtggccatcaaggaattgaga gaagccacgtctccgaaagccaacaaggagattctcgatgaagcctacgtgatggccagc gtggaccacccccatgtgtgccgcctgctgggcatctgcctgacctccacggtgcagctc atcacccagctcatgcccttcggctgcctgctggactacgtccgcgagcacaaggacaac atcggctcccagtacctgctcaactggtgtgtgcagatcgccaagggcatgaactacctg gaggaccggcgcctggtgcaccgggacctggcggccaggaatgtcctggtgaagacaccg cagcacgtcaagatcaccgacttcgggctggccaaactgctgggcgcggaggagaaagag taccacgcagaggggggcaaagtgcccatcaagtggatggctttggagtctattttacac cgaatttatacccaccaaagtgacgtctggagctatggggtcaccgtttgggagctgatg acctttgggtccaagccttacgacgggatcccggcgagtgagatctccaccgtcctggag aaaggagagcgcctcccgcagccgcccatctgcaccattgacgtctacatgatcatggtc aagtgctggatgatagacgcagacagccgcccgaagttccgggagctgatccatgaattc tccaagatggcccgggacccccagcgctaccttgtcatccagggggatgagagaatgcac ctgcccagccctaccgactccaacttctaccgcgccctgatggacgaagaggacatggag gacgttgtcgacgccgacgagtacctcatcccccagcaggccttcttccacagcccctcc acctcccggacgccccttctgagctccctgagcgccaccagcaacagctccactgtggcg tgcgctgacagaaacgggcagagctgccccctgaaggaagacagcttcttgcagcggtac agctccgaccccaccggggccttgaccgaggacgtcatcaacggcactttcctcccagcg ccagaatacataaaccagttggttcccaaaaggccggcgggctccgtccagaaccccgtc taccacaatcaacccctaaacctggctccaggccgagaccctcactaccagaacccccac agcaacgccgtgggcaaccccgagtatctcaacaccacccctcctcccaccgtcaacggc gtccccgatggccccaccctctgggtgcagaaaggcagccaccagattagcctggacaac cccgactaccaacaggacttcttccccagggaagccaagtccaatggcatctttaagggg ccgacagctgaaaatgcagactacctgagggtaggcgccccgagcagtgaatttatcgga gcatga

DBGET integrated database retrieval system