Desmodus rotundus (common vampire bat): 112308428
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Entry
112308428 CDS
T05907
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
dro
Desmodus rotundus (common vampire bat)
Pathway
dro00260
Glycine, serine and threonine metabolism
dro00630
Glyoxylate and dicarboxylate metabolism
dro00670
One carbon pool by folate
dro01100
Metabolic pathways
dro01200
Carbon metabolism
dro01230
Biosynthesis of amino acids
dro01240
Biosynthesis of cofactors
dro01523
Antifolate resistance
Module
dro_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
dro00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
112308428 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
112308428 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
112308428 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
112308428 (SHMT1)
Enzymes [BR:
dro01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
112308428 (SHMT1)
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Paralog
GFIT
Motif
Pfam:
SHMT
Aminotran_1_2
DegT_DnrJ_EryC1
Motif
Other DBs
NCBI-GeneID:
112308428
NCBI-ProteinID:
XP_024420408
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All DBs
Position
Unknown
AA seq
484 aa
AA seq
DB search
MATEVNRAPKDADLWRSHDKMLAQPLKDNDIEVYNIIKKESKRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQRRALQVYGLDPQCWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
INYDQLEENARLFHPKLIIAGTSSYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGV
VPSPFEHCHVVSTTTHKTLRGCRAGMIFYRRGVCGMDPKTGKEILYNLESLINSAVFPGL
QGGPHNHAIAGVAVALKQALTPEFRLYQHQVVANCRVLAETLMELGYKVVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKEFQK
VALFIHQGIELTLQIQNDVGVKATLKEFKEKLAGDEKHLSAIRALREEVESFASLFPLPG
LLDS
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atggcgactgaggtcaacagggctcccaaggatgccgacctgtggcgctcgcatgataaa
atgttggcacagccgctgaaagacaacgacatagaggtttacaacatcattaagaaggaa
agcaaacggcagagggttggattagagctgatcgcttcagagaatttcgccagcagagca
gttttggaggcccttggctcttgcctaaataacaagtactctgaggggtacccaggccag
aggtattacggtggcaccgagtttatcgatgagctggagaccctctgtcagaggcgagcg
ctgcaggtctatggtctggacccccagtgctggggagtcaacgtccagccctactcaggg
tcccctgccaactttgcagtgtacactgccctggtagaaccccatggacgcatcatgggc
ctggatctgcccgatggaggccatctgacccacgggttcatgacagataagaagaaaatc
tctgctacgtccatcttttttgaatctatgccctacaaggtgaacccagacaccggctac
atcaactatgaccagctggaggagaacgcccgcctcttccacccgaagctgattattgca
ggaaccagctcctactcccgaaacctggactacgctcgattgcggaagattgccgatgac
aacggggcgtacctcatggccgacatggcacacatcagcgggctggtggcagctggagtg
gtgccctccccctttgaacactgccacgtggtgtccaccaccacccacaaaaccctgaga
ggctgccgagctggcatgatcttctacaggcgaggagtgtgcggcatggatcccaaaact
ggcaaagagatcctgtacaacctggagtcgctcatcaactccgctgtgttcccaggactg
cagggaggcccccacaaccacgccattgctggggtcgctgtggctctgaagcaagccctg
actccagaattcagactttatcagcaccaggtggtggccaactgcagggttctggctgag
actttgatggagctgggctacaaagtagtaacaggtggttctgacaaccatttgatcctc
gtggatctccgttccaaaggcacggatggtggcagggctgagaaggtgctagaagcctgt
tctattgcctgcaacaagaacacctgcccaggtgacaaaagcgcactgcggcccagtggg
ctgcgactggggaccccagcactgacgtctcgaggacttctggaaaaagagttccaaaaa
gtagccctcttcattcaccaagggatagaactgactctgcagattcagaacgacgttggt
gtcaaggccaccctgaaggagttcaaggagaaactggcaggggatgagaagcaccttagc
gccatcagagctctcagggaggaggtggagagctttgcgtctcttttccctctgccaggc
ctgcttgactcttag
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