Desmodus rotundus (common vampire bat): 112316288
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Entry
112316288 CDS
T05907
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
dro
Desmodus rotundus (common vampire bat)
Pathway
dro04140
Autophagy - animal
dro04141
Protein processing in endoplasmic reticulum
dro04210
Apoptosis
dro04932
Non-alcoholic fatty liver disease
dro05010
Alzheimer disease
dro05012
Parkinson disease
dro05014
Amyotrophic lateral sclerosis
dro05016
Huntington disease
dro05017
Spinocerebellar ataxia
dro05022
Pathways of neurodegeneration - multiple diseases
dro05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
dro00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
112316288 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
112316288 (ERN1)
09143 Cell growth and death
04210 Apoptosis
112316288 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
112316288 (ERN1)
05012 Parkinson disease
112316288 (ERN1)
05014 Amyotrophic lateral sclerosis
112316288 (ERN1)
05016 Huntington disease
112316288 (ERN1)
05017 Spinocerebellar ataxia
112316288 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
112316288 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
112316288 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
112316288 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dro01001
]
112316288 (ERN1)
Enzymes [BR:
dro01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
112316288 (ERN1)
Protein kinases [BR:
dro01001
]
Serine/threonine kinases: Other
IRE family
112316288 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
PAP1
Motif
Other DBs
NCBI-GeneID:
112316288
NCBI-ProteinID:
XP_024428872
LinkDB
All DBs
Position
Unknown
AA seq
876 aa
AA seq
DB search
MDQVWLLSFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQVPTHVEEP
AFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQDIWYVIDLL
TGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDYAASLPEDDV
DYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMHINVAVETLR
YLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVPRGS
TLPLLEGPQTDGVTIGDKGECVITPSTDLKFNPGLKGKNKLNYLRNYWLLIGHHETPLSA
STKMLERFPNNLPRHRGNVIPADSEKKSFEEVIHLVDQNSENAPTTVSQDVEEKFAHAPA
KPEAPMDSMLKDIATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQKELEKIQLLHQ
QQLPFHAPGDMAQDAELLDSSGLYSESSGTSSPSTSPRASNHSLHSTGSASKTSTGPFLE
QDDGDEETSMVMVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREV
QLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQQTT
SGLAHLHSLNIVHRDLKPHNILLSMPNAHGKIKAMISDFGLCKKLAVGRHSFSRRSGVPG
TEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGAYSLD
CLHPEKHGEQAGGAGGVGANPQLPPWPLRLGWCLLHVPRDPSLPPPTCGWEGLFLEHLLL
KPRNSEFPSGHPINYLCDGVRPPLGTSVFRLATWEG
NT seq
2631 nt
NT seq
+upstream
nt +downstream
nt
atggatcaagtctggcttcttagttttggaagtcccagcacagtgacgcttcctgagacc
ttgttgtttgtgtcgaccctggacgggagtttgcatgctgtcagcaagaggacaggctcg
atcaaatggacgttaaaagaagatccagttctgcaggttccaacacacgtggaagagcct
gccttcctcccagaccccaacgacggcagcctctacacacttgggggcaagaataacgaa
ggcctgacgaaacttccctttaccatcccggagttggttcaggcatccccatgccgaagt
tcagatgggattctctacatgggtaaaaagcaggacatttggtatgtcatcgaccttctg
accggagagaagcagcagactttgtcatcggcctttgcagatagtctctgtccttcgacc
tctcttctgtatctcgggcgaacagaatacaccatcaccatgtacgacaccaagacccga
gagctccggtggaacgccacctacttcgactacgcagcctcgctgccggaggatgacgtg
gactacaagatgtcccactttgtgtccaatggcgacgggctggtggtgactgtggacagt
gaatctggtgacgtcctgtggatccagaactatgcctcccctgtggtggccttttatgtc
tggcagcgggagggcctgaggaaggtgatgcatatcaacgtcgcggtagagaccctgcgc
tacctgaccttcatgtccggggaggtgggacgcatcaccaagtggaagtaccccttcccc
aaggagacggaggccaagagcaagctgacgcccaccttgtatgttgggaaatactctact
agcctctacgcctccccctcaatggtccacgagggtgttgccgttgtgccccgaggtagc
actcttcctttgctggaaggtccccagacagacggtgtcaccattggggacaaaggggag
tgtgtgatcacacccagcacagacctaaagtttaatcctgggctcaaaggaaagaacaag
ctcaactacctgaggaactactggcttctaatcgggcaccacgaaaccccgctgtccgcg
tctaccaagatgctggagagattccccaacaacctgcccagacaccggggaaatgtcatt
cctgcggactcagagaaaaagagctttgaggaagtcatccacctggttgatcagaattca
gagaatgcgcccaccaccgtttctcaggatgtggaggaaaagttcgctcatgcccccgcc
aagcctgaggcccccatggactccatgctcaaggacatagccaccatcatcctgagcacc
ttcctgctcatcggctgggtggccttcatcatcacctaccccctgagcatgcatcagcag
cagcagctccagcaccagcagttccagaaggaactagaaaaaatccagctcctgcaccag
cagcagctgcccttccatgcacctggagacatggctcaggatgcggagctcctggactcg
tctggcctgtactcggagagctcgggcaccagcagccccagcacgtcccccagagcctcc
aaccactcgctccactccactggctctgcctccaagactagcaccggcccgtttctggag
caggatgacggggacgaggaaaccagcatggtgatggttggaaaaatctcattctgcccc
aaggacgtcctaggccacggagccgagggcaccattgtgtaccggggcatgtttgacaac
cgcgacgtggcggtcaagaggatcctccccgagtgcttcagttttgccgaccgagaggtc
cagctgctgcgggagtctgatgagcacccgaatgtgatccgttacttctgtaccgagagg
gaccggcagttccagtacatcgccatcgagctatgcgcagccacgctgcaggagtacgtg
gagcagaaagacttcgcccacctcggcctggagcccatcaccttgctgcagcagaccacc
tcggggctggcccacctgcactccctcaacattgtccacagagacctgaagccccacaac
atcctcctctccatgcccaatgcgcacggcaagatcaaggccatgatctccgactttggc
ctctgcaagaagctggcagtgggcaggcacagcttcagccgccgttcgggggtgcctggc
acggaaggctggatcgccccggagatgctgagtgaggactgcaaggagaaccccacctac
acagtggacatcttctctgcgggctgcgtcttttactacgtgatctctgagggcagccac
cctttcggcaagtccctgcagcggcaagctaacatcctcctgggcgcctacagcctcgac
tgcttacaccccgagaagcacggtgagcaggcaggaggggcgggaggggtgggagccaat
cctcagctgcccccatggcccctgcggttggggtggtgcctgctccatgttcccagagat
ccttctctcccgccgcccacctgtggctgggaggggctcttcttggagcacctcctccta
aagccaagaaactctgagtttccttcaggccacccaattaattacctgtgtgacggggta
agaccccctttgggaacctctgttttccggcttgcgacttgggagggttaa
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integrated database retrieval system
