KEGG T05907: 112316527

KEGG Orthology (KO) [BR:dro00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    112316527 (RPS6KB1)
   04350 TGF-beta signaling pathway
    112316527 (RPS6KB1)
   04371 Apelin signaling pathway
    112316527 (RPS6KB1)
   04066 HIF-1 signaling pathway
    112316527 (RPS6KB1)
   04151 PI3K-Akt signaling pathway
    112316527 (RPS6KB1)
   04152 AMPK signaling pathway
    112316527 (RPS6KB1)
   04150 mTOR signaling pathway
    112316527 (RPS6KB1)
09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    112316527 (RPS6KB1)
09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    112316527 (RPS6KB1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    112316527 (RPS6KB1)
  09149 Aging
   04211 Longevity regulating pathway
    112316527 (RPS6KB1)
   04213 Longevity regulating pathway - multiple species
    112316527 (RPS6KB1)
  09159 Environmental adaptation
   04714 Thermogenesis
    112316527 (RPS6KB1)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112316527 (RPS6KB1)
   05205 Proteoglycans in cancer
    112316527 (RPS6KB1)
   05231 Choline metabolism in cancer
    112316527 (RPS6KB1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    112316527 (RPS6KB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    112316527 (RPS6KB1)
   05212 Pancreatic cancer
    112316527 (RPS6KB1)
   05225 Hepatocellular carcinoma
    112316527 (RPS6KB1)
   05226 Gastric cancer
    112316527 (RPS6KB1)
   05221 Acute myeloid leukemia
    112316527 (RPS6KB1)
   05224 Breast cancer
    112316527 (RPS6KB1)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    112316527 (RPS6KB1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    112316527 (RPS6KB1)
   05163 Human cytomegalovirus infection
    112316527 (RPS6KB1)
   05165 Human papillomavirus infection
    112316527 (RPS6KB1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    112316527 (RPS6KB1)
   01522 Endocrine resistance
    112316527 (RPS6KB1)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dro01001]
    112316527 (RPS6KB1)
Enzymes [BR:dro01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     112316527 (RPS6KB1)
Protein kinases [BR:dro01001]
Serine/threonine kinases: AGC group
  RSK family [OT]
   112316527 (RPS6KB1)

SSDB

Motif

Pfam:

Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal APH

Other DBs

NCBI-GeneID:

112316527

NCBI-ProteinID:

XP_024429166

LinkDB

Position

Unknown

AA seq 525 aa
MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG
PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF
AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL
FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC
KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK
TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL
LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE
SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSG
IEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL

NT seq 1578 nt +upstreamnt +downstreamnt
atgaggcgacgacggaggcgggacggcttttacccagcgccggacttccgagacagggaa
gctgaggacatggcaggagtgtttgacatagacctggaccagccagaagacgcgggctct
gaggatgagctggaggaggggggtcagttaaatgaaagcatggaccatgggggagttgga
ccatatgaacttggcatggaacattgtgagaaatttgaaatctcagaaactagtgtgaac
agagggccagaaaaaatcagaccagaatgttttgagctacttcgggtacttggtaaaggg
ggctatggaaaggttttccaagtacgaaaagtaacaggagcaaatactgggaaaatattt
gccatgaaggtgcttaaaaaggcaatgatagtaagaaatgctaaagatacagctcataca
aaagcagaacggaatattctggaggaagtaaagcatcccttcattgtggatttaatttat
gcctttcagactggtggaaaactctacctcatccttgagtatctcagcggaggagaatta
tttatgcagttagaaagagagggaatatttatggaagacacagcctgcttttacttggca
gaaatctccatggctttggggcatttacatcaaaaggggatcatctacagagacctgaag
ccggagaatatcatgcttaatcaccaaggtcacgtgaaactaacagactttggactatgc
aaagaatctattcatgatggaacagtcacacacacattttgtggaacaatagaatacatg
gcccctgaaatcttgatgcgaagtggccacaatcgtgctgtggattggtggagtttggga
gcattaatgtatgacatgctgactggagcacccccgttcactggggagaatagaaagaaa
acgattgacaaaatcctcaaatgtaaactcaatttgcctccctacctcacacaagaagcc
agagatctgcttaaaaagctgctgaaaagaaatgctgcttctcgtctcggagctggtcct
ggggatgctggagaagttcaagctcatccatttttcagacatattaactgggaagaattg
ctggctcggaaggtggagcccccctttaaacctctattgcaatctgaagaggacgtgagt
cagtttgattcaaagtttacacgtcagacgcctgttgacagcccggatgactcaactctc
agtgaaagtgccaaccaggtctttctgggttttacatatgtggctccatctgtacttgaa
agcgtgaaagaaaagttttcctttgaaccaaaaatccgatcacctcgaagatttattggc
agcccacgaacacctgtcagcccagtcaaattttctcctggggatttctggggaagaggt
gcttcagccagcacagcaaatcctcagacgcctgtggaatacccaatggaaacgagtgga
atagagcagatggatgtgacgatgagtggggaagcttcagccccacttccaatacgacag
ccgaactccgggccatacaaaaaacaagcttttcccatgatctccaaacgaccagagcac
ctacgtatgaatctatga

Desmodus rotundus (common vampire bat): 112317229

Entry

112317229 CDS T05907

Gene name

RPS6KB2

Definition

(RefSeq) ribosomal protein S6 kinase beta-2

K04688

ribosomal protein S6 kinase beta [EC:2.7.11.1]

Organism

dro Desmodus rotundus (common vampire bat)

Pathway

dro01521

EGFR tyrosine kinase inhibitor resistance

dro01522

Endocrine resistance

dro04012

ErbB signaling pathway

dro04066

HIF-1 signaling pathway

dro04140

Autophagy - animal

dro04150

mTOR signaling pathway

dro04151

PI3K-Akt signaling pathway

dro04152

AMPK signaling pathway

dro04211

Longevity regulating pathway

dro04213

Longevity regulating pathway - multiple species

dro04350

TGF-beta signaling pathway

dro04371

Apelin signaling pathway

dro04666

Fc gamma R-mediated phagocytosis

dro04714

Thermogenesis

dro04910

Insulin signaling pathway

dro04931

Insulin resistance

dro05163

Human cytomegalovirus infection

dro05165

Human papillomavirus infection

dro05170

Human immunodeficiency virus 1 infection

dro05200

Pathways in cancer

dro05205

Proteoglycans in cancer

dro05210

Colorectal cancer

dro05212

Pancreatic cancer

dro05221

Acute myeloid leukemia

dro05224

Breast cancer

dro05225

Hepatocellular carcinoma

dro05226

Gastric cancer

dro05231

Choline metabolism in cancer

dro05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

Brite

KEGG Orthology (KO) [BR:dro00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    112317229 (RPS6KB2)
   04350 TGF-beta signaling pathway
    112317229 (RPS6KB2)
   04371 Apelin signaling pathway
    112317229 (RPS6KB2)
   04066 HIF-1 signaling pathway
    112317229 (RPS6KB2)
   04151 PI3K-Akt signaling pathway
    112317229 (RPS6KB2)
   04152 AMPK signaling pathway
    112317229 (RPS6KB2)
   04150 mTOR signaling pathway
    112317229 (RPS6KB2)
09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    112317229 (RPS6KB2)
09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    112317229 (RPS6KB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    112317229 (RPS6KB2)
  09149 Aging
   04211 Longevity regulating pathway
    112317229 (RPS6KB2)
   04213 Longevity regulating pathway - multiple species
    112317229 (RPS6KB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    112317229 (RPS6KB2)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112317229 (RPS6KB2)
   05205 Proteoglycans in cancer
    112317229 (RPS6KB2)
   05231 Choline metabolism in cancer
    112317229 (RPS6KB2)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    112317229 (RPS6KB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    112317229 (RPS6KB2)
   05212 Pancreatic cancer
    112317229 (RPS6KB2)
   05225 Hepatocellular carcinoma
    112317229 (RPS6KB2)
   05226 Gastric cancer
    112317229 (RPS6KB2)
   05221 Acute myeloid leukemia
    112317229 (RPS6KB2)
   05224 Breast cancer
    112317229 (RPS6KB2)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    112317229 (RPS6KB2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    112317229 (RPS6KB2)
   05163 Human cytomegalovirus infection
    112317229 (RPS6KB2)
   05165 Human papillomavirus infection
    112317229 (RPS6KB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    112317229 (RPS6KB2)
   01522 Endocrine resistance
    112317229 (RPS6KB2)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dro01001]
    112317229 (RPS6KB2)
Enzymes [BR:dro01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     112317229 (RPS6KB2)
Protein kinases [BR:dro01001]
Serine/threonine kinases: AGC group
  RSK family [OT]
   112317229 (RPS6KB2)

SSDB

Motif

Pfam:

Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal Seadorna_VP7 Kdo

Other DBs

NCBI-GeneID:

112317229

NCBI-ProteinID:

XP_024430072

LinkDB

Position

Unknown

AA seq 482 aa
MAAVFDLDLETEEDSEGEGEPEFPADVCPLAELRAAGLEPVGHCEEVELTETSVNPSPER
IGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVCNAKDTAHTRAERN
ILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLGEITLA
LGHLHSQGIIYRDLKPENIMLNSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEVL
ARSGHSWAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLALPPYLTPDARDLIK
KFLKRNPSQRIGGGPGDAADVQRHPFFRHINWDDLLARRMDPPFRPCLQSEEDVSQFDTR
FTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFTFQPKLRSPRRLNSSPRTP
ISPLKFSPFEGFRPSSGPPEPMEPPLPPLMPPPPPPSSTVPLPIRLPSGTKKSKRGRGRP
GR

NT seq 1449 nt +upstreamnt +downstreamnt
atggcggccgtgtttgacctggatctggagacggaggaagacagcgagggcgagggcgag
ccagagttccctgcggacgtgtgtccccttgccgagttgagggcggctggcctggagcct
gtgggacactgtgaggaggtggagctgactgagaccagtgtgaaccctagccctgagcgc
attgggccccactgctttgagctgctgcgtgtgctgggcaaggggggctatggcaaggtg
ttccaggtgcgaaaggtgcagggcaccaacttgggcaaaatatatgccatgaaagtcctg
aggaaggccaaaatcgtgtgcaacgccaaggacacagcacacacacgggccgagcggaac
attctggagtctgtgaagcatcccttcattgtggagctggcctatgccttccagactggc
ggcaagctctacctcatcctcgagtgcctcagtggcggtgagctcttcacgcacttggag
cgagagggcatcttcctggaagacacagcctgcttctacctgggagagatcacactggcc
ctgggccacctgcactcccagggcatcatctaccgggacctcaaacccgagaacatcatg
ctgaacagccagggccacatcaaactgacagattttgggctctgcaaggagtcgattcac
gagggtgccgtcacccacaccttctgtggcaccattgagtacatggcccctgaggtcctg
gcgcgcagcggccacagctgggcagtggactggtggagcctgggggccctgatgtacgac
atgctcactggatcgccgcccttcactgcagagaaccggaagaaaaccatggacaagatc
atcaaagggaagctggcgctgcccccgtacctcaccccggatgcccgggacctcatcaaa
aagtttctgaagcggaatcccagccagcggattgggggtggcccaggggacgctgctgat
gtgcagaggcacccctttttccggcacattaattgggatgatctcctggcccgccgcatg
gacccccctttcaggccctgtctgcagtcggaggaggacgtgagccagtttgacacccgc
ttcacacggcagacgccggtggacagtccagacgacacggccctcagcgagagtgccaac
caggctttcctgggcttcacatacgtggcgccctctgtcctggacagcatcaaggagggc
ttcaccttccagcccaagctgcgctccccccggcgcctcaacagcagcccccggactcct
atcagccccctgaagttctcaccctttgaggggttccgacccagctctggaccaccagag
cccatggagccccctctgcctcctctgatgccaccaccgccaccaccctcaagcactgtc
cccctccccatccgactgccctcagggaccaagaagtccaagaggggccgcgggcgccct
gggcgctaa

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