KEGG   DISEASE: Enteropathogenic Escherichia coli (EPEC) infection
Entry
H00278                      Disease                                

Name
Enteropathogenic Escherichia coli (EPEC) infection
Description
Enteropathogenic Escherichia coli (EPEC) was the first pathotype of E. coli identified in the 1940s, and remains a common cause of infantile diarrhea in developing countries. EPEC and EHEC [DS:H00277] strains are characterized by the type III secretion system and its cognate effectors encoded in the locus of enterocyte effacement (LEE), but EPEC does not release diffusible toxins.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by enterobacteria
   H00278  Enteropathogenic Escherichia coli (EPEC) infection
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Gastroenteritis or colitis of infectious origin
   Bacterial intestinal infections
    1A03  Intestinal infections due to Escherichia coli
     H00278  Enteropathogenic Escherichia coli (EPEC) infection
Pathway
hsa05130  Pathogenic Escherichia coli infection
Network
  Element
N00926  Escherichia Tir to TLR2/4-MAPK signaling pathway
N00927  Escherichia/Shigella NleE/OspZ to TNF-NFKB signaling pathway
N00928  Escherichia NleB to TNF-NFKB signaling pathway
N00929  Escherichia NleC to TNF-NFKB signaling pathway
N00930  Escherichia NleD to TNF-JNK signaling pathway
N00931  Escherichia NleD to TNF-p38 signaling pathway
N00932  Escherichia NleH1 to TNF-NFKB signaling pathway
N00933  Escherichia NleA to NLRP3 inflammasome signaling pathway
N00935  Escherichia NleF to non-canonical inflammasome signaling pathway
N00936  Escherichia NleB1 to crosstalk between extrinsic and intrinsic apoptotic pathways
N00937  Escherichia NleF to extrinsic apoptotic pathway
N00938  Escherichia NleH to intrinsic apoptotic pathway
N00939  Escherichia EspF to intrinsic apoptotic pathway
N01084  Escherichia EspG to ARNO-ARF-ACTB/G signaling pathway
N01085  Escherichia EspG to ARNO-ARF-ACTB/G signaling pathway
N01086  Escherichia EspT to RAC signaling pathway
N01087  Escherichia EspW to RAC signaling pathway
N01088  Escherichia EspH to LPA-GNA12/13-RhoA signaling pathway
N01089  Escherichia EspM to LPA-GNA12/13-Rho signaling pathway
N01091  Escherichia EspJ to IGG-FCGR-RAC signaling pathway
N01092  Escherichia Eae/Tir to Actin signaling pathway
N01093  Escherichia EspJ/Tir to Actin signaling pathway
N01094  Escherichia Eae/Tir/TccP to Actin signaling pathway
N01095  Escherichia Map to LPA-GNA12/13-RhoA signaling pathway
N01096  Escherichia Map to CDC42 signaling pathway
N01286  Escherichia EspG to Microtubule-RHOA signaling pathway
N01288  Escherichia EspF to Tight junction-Actin signaling pathway
N01290  Escherichia NleA to COPII vesicle formation
N01292  Escherichia EspG to RAB1 signaling pathway
N01294  Escherichia NleF to COPI vesicle formation
Pathogen
Escherichia coli O127:H6 [GN:ecg]
Escherichia coli O55:H7 [GN:eok elr]
  Module
M00542  EHEC/EPEC pathogenicity signature, T3SS and effectors
Other DBs
ICD-11: 1A03.0
ICD-10: A04.0
MeSH: D004927
Reference
  Authors
Ochoa TJ, Barletta F, Contreras C, Mercado E
  Title
New insights into the epidemiology of enteropathogenic Escherichia coli infection.
  Journal
Trans R Soc Trop Med Hyg 102:852-6 (2008)
DOI:10.1016/j.trstmh.2008.03.017
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