KEGG   DISEASE: YersiniosisHelp
Entry
H00298                      Disease                                

Name
Yersiniosis
Description
Yersiniosis (non-plague) is an infectious disease caused by two species, Yersinia enterocolitica and Y. pseudotuberculosis, which is zoonotic, capable of being transmitted from infected animals to man. Major clinical forms include acute gastroenteritis and mesenteric lymphadenitis, which are often accompanied by fever and abdominal pain. Routes of transmission include fecal-oral spread via ingestion of contaminated food as the most common route and consumption of contaminated water supplies. Yersiniosis occurs more commonly in regions with temperate rather than tropical or subtropical climates.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by enterobacteria
   H00298  Yersiniosis
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Gastroenteritis or colitis of infectious origin
   Bacterial intestinal infections
    1A05  Intestinal infections due to Yersinia enterocolitica
     H00298  Yersiniosis
  Certain zoonotic bacterial diseases
   1B9A  Extraintestinal yersiniosis
    H00298  Yersiniosis
BRITE hierarchy
Pathway
hsa05135 Yersinia infection   
Network
  Element
N00859  Yersinia YopP/J to TLR2/4-NFKB signaling pathway
N00860  Yersinia YopP/J to TLR2/4-NFKB signaling pathway
N00861  Yersinia YopP/J to TLR2/4-NFKB signaling pathway
N00862  Yersinia YopP/J to TLR2/4-MAPK signaling pathway
N00863  Yersinia YopM to NLRP3 Inflammasome signaling pathway
N00864  Yersinia YopK to NLRP3 Inflammasome signaling pathway
N00865  Yersinia YopK to NLRC4 Inflammasome signaling pathway
N00866  Yersinia YopM to Pyrin Inflammasome signaling pathway
Pathogen
Yersinia pseudotuberculosis [GN:yps ypi]
Yersinia enterocolitica [GN:yen yep yey yef]
superantigen [KO:K11010]
Other DBs
ICD-11: 1A05 1B9A
ICD-10: A04.6 A28.2
MeSH: D015009
Reference
  Authors
Smego RA, Frean J, Koornhof HJ
  Title
Yersiniosis I: microbiological and clinicoepidemiological aspects of plague and non-plague Yersinia infections.
  Journal
Eur J Clin Microbiol Infect Dis 18:1-15 (1999)
DOI:10.1007/s100960050219
Reference
  Authors
Pujol C, Bliska JB
  Title
Turning Yersinia pathogenesis outside in: subversion of macrophage function by intracellular yersiniae.
  Journal
Clin Immunol 114:216-26 (2005)
DOI:10.1016/j.clim.2004.07.013
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