KEGG   DISEASE: Chancroid
Entry
H00305                      Disease                                

Name
Chancroid
Description
Chancroid is a sexually transmitted disease (STD) caused by the gram-negative, short, slender bacterium Haemophilus ducreyi. It is a classical genito-ulcerative disease accompanied by inguinal lymphadenitis that is endemic in sub-Saharan Africa. It has generated considerable interest because it is associated as a co-factor for HIV transmission.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by other gamma proteobacteria
   H00305  Chancroid
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Predominantly sexually transmitted infections
   1A90  Chancroid
    H00305  Chancroid
Pathogen
Haemophilus ducreyi [GN:hdu]
cytolethal distending toxin [KO:K11013 K11014 K11015]
Drug
Tetracycline hydrochloride [DR:D02122]
Doxycycline [DR:D00307]
Doxycycline hyclate [DR:D02129]
Doxycycline calcium [DR:D03903]
Minocycline hydrochloride [DR:D00850]
Streptomycin sulfate [DR:D01350]
Demeclocycline hydrochloride [DR:D00290]
Sulfadiazine [DR:D00587]
Comment
Pregnant women should be treated with either erythromycin or ceftriaxone regimens.
Other DBs
ICD-11: 1A90
ICD-10: A57
MeSH: D002602
MedlinePlus: 000635
Reference
  Authors
Lewis DA
  Title
Chancroid: clinical manifestations, diagnosis, and management.
  Journal
Sex Transm Infect 79:68-71 (2003)
DOI:10.1136/sti.79.3.228
Reference
  Authors
Sehgal VN, Srivastava G
  Title
Chancroid: contemporary appraisal.
  Journal
Int J Dermatol 42:182-90 (2003)
DOI:10.1046/j.1365-4362.2003.01724.x
Reference
  Authors
Annan NT, Lewis DA
  Title
Treatment of chancroid in resource-poor countries.
  Journal
Expert Rev Anti Infect Ther 3:295-306 (2005)
DOI:10.1586/14787210.3.2.295
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