KEGG   DISEASE: Meningococcal infection
Entry
H00314                      Disease                                
Name
Meningococcal infection
Description
Neisseria meningitidis is a gram-negative bacterial pathogen that specifically infects humans. It is a frequent asymptomatic colonizer of the human upper respiratory tract, and most adults are resistant to infection through acquired immunity. In susceptible individuals, it causes meningococcal meningitis and severe septicemia.
Category
Bacterial infectious disease
Brite
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Other bacterial diseases
   1C1C  Meningococcal disease
    H00314  Meningococcal infection
Genome-based classification of infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by beta proteobacteria
   H00314  Meningococcal infection
Pathogen
Neisseria meningitidis serogroup A [GN:nma nmw nmx]
Neisseria meningitidis serogroup B [GN:nme nmh nmd nmm nms nmq nmz]
Neisseria meningitidis serogroup C [GN:nmc nmn nmt]
Drug
Penicillin G potassium [DR:D01053]
Sulfadiazine [DR:D00587]
Comment
Antibiotic resistance in N. meningitidis ash been reported.
Other DBs
ICD-11: 1C1C
ICD-10: A39
MeSH: D008589
Reference
PMID:19287450
  Authors
Virji M
  Title
Pathogenic neisseriae: surface modulation, pathogenesis and infection control.
  Journal
Nat Rev Microbiol 7:274-86 (2009)
DOI:10.1038/nrmicro2097
Reference
PMID:12150701
  Authors
Foster C, Nadel S
  Title
New therapies and vaccines for bacterial meningitis.
  Journal
Expert Opin Investig Drugs 11:1051-60 (2002)
DOI:10.1517/13543784.11.8.1051
Reference
PMID:22085175
  Authors
Safadi MA, McIntosh ED
  Title
Epidemiology and prevention of meningococcal disease: a critical appraisal of vaccine policies.
  Journal
Expert Rev Vaccines 10:1717-30 (2011)
DOI:10.1586/erv.11.159
Reference
PMID:21832882
  Authors
Yogev R, Tan T
  Title
Meningococcal disease: the advances and challenges of meningococcal disease prevention.
  Journal
Hum Vaccin 7:828-37 (2011)
DOI:10.4161/hv.7.8.16270
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