KEGG   DISEASE: Pseudomembranous colitis
Entry
H00338                      Disease                                

Name
Pseudomembranous colitis
  Supergrp
Anaerobic infection [DS:H01410]
Description
Clostridium difficile is a gram-positive anaerobic bacillus that causes a broad spectrum of clinical symptoms ranging from mild diarrhea to severe pseudomembranous colitis. C. difficile can be transmitted by the fecal-oral route from person to person and instrument to patient.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by Gram-positive bacteria
   H00338  Pseudomembranous colitis
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Gastroenteritis or colitis of infectious origin
   Bacterial intestinal infections
    1A04  Enterocolitis due to Clostridium difficile
     H00338  Pseudomembranous colitis
Pathogen
Clostridioides difficile [GN:cdf pdc cdc cdl]
toxin A/B [KO:K11063]
pore-forming toxin [KO:K06442 K11068]
Drug
Fidaxomicin [DR:D09394]
Bezlotoxumab [DR:D10453]
Other DBs
ICD-11: 1A04
ICD-10: A04.7
MeSH: D004761
MedlinePlus: 000259
Reference
(drug)
  Authors
Papadakis MA and McPhee SJ |(ed)
  Title
Current Medical Diagnosis & Treatment 2007, Forty-Sixth Edition
  Journal
McGraw Hill Education
Reference
  Authors
Kachrimanidou M, Malisiovas N
  Title
Clostridium difficile infection: a comprehensive review.
  Journal
Crit Rev Microbiol 37:178-87 (2011)
DOI:10.3109/1040841X.2011.556598
Reference
  Authors
Elliott B, Chang BJ, Golledge CL, Riley TV
  Title
Clostridium difficile-associated diarrhoea.
  Journal
Intern Med J 37:561-8 (2007)
DOI:10.1111/j.1445-5994.2007.01403.x
Reference
  Authors
Bouza E, Munoz P, Alonso R
  Title
Clinical manifestations, treatment and control of infections caused by Clostridium difficile.
  Journal
Clin Microbiol Infect 11 Suppl 4:57-64 (2005)
DOI:10.1111/j.1469-0691.2005.01165.x
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