KEGG   DISEASE: Lyme borreliosis
Entry
H00353                      Disease                                

Name
Lyme borreliosis;
Lyme disease
Description
Lyme borreliosis is the multisystem infectious disease caused by the tick-borne spirochetes Borrelia. Localized infection is typically manifested by erythema migrans skin lesions. A broad variety of peripheral nerve disorders (Lyme neuroborreliosis) can occur as well. Late Lyme borreliosis usually manifests as arthritis or the skin disorder known as acrodermatitis chronica atrophicans.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by spirochaetes
   H00353  Lyme borreliosis
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Other bacterial diseases
   1C1G  Lyme borreliosis
    H00353  Lyme borreliosis
Pathogen
Borrelia burgdorferi (Lyme disease) [GN:bbu bbz bbn bbj]
Borrelia garinii [GN:bga bgb bgc]
Borrelia afzelii [GN:baf bafz bafh bafe]
Borrelia bissettii [GN:bbs]
Borrelia mayonii [GN:bmay]
Drug
Doxycycline hyclate [DR:D02129]
Cefuroxime axetil [DR:D00914]
Comment
Vector: Ixodes sp. (tick)
Other DBs
ICD-11: 1C1G
ICD-10: A69.2
MeSH: D008193
MedlinePlus: 001319
Reference
  Authors
Stanek G, Wormser GP, Gray J, Strle F
  Title
Lyme borreliosis.
  Journal
Lancet 379:461-73 (2012)
DOI:10.1016/S0140-6736(11)60103-7
Reference
  Authors
Halperin JJ
  Title
Lyme disease and the peripheral nervous system.
  Journal
Muscle Nerve 28:133-43 (2003)
DOI:10.1002/mus.10337
Reference
  Authors
Zajkowska J, Czupryna P, Pancewicz SA, Kondrusik M, Moniuszko A
  Title
Acrodermatitis chronica atrophicans.
  Journal
Lancet Infect Dis 11:800 (2011)
DOI:10.1016/S1473-3099(10)70121-3
Reference
  Authors
Glockner G, Lehmann R, Romualdi A, Pradella S, Schulte-Spechtel U, Schilhabel M, Wilske B, Suhnel J, Platzer M.
  Title
Comparative analysis of the Borrelia garinii genome.
  Journal
Nucleic Acids Res 32:6038-46 (2004)
DOI:10.1093/nar/gkh953
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