KEGG   DISEASE: Malaria
Entry
H00361                      Disease                                

Name
Malaria
Description
Malaria, the most common parasitic disease in the world, is caused by Plasmodium parasites that are transmitted by female Anopheline mosquitoes. Plasmodium infections result in a spectrum of clinical effects, including asymptomatic parasitemia, severe malaria, and death. Most severe cases occur in sub-Saharan Africa. In severe malaria, complications such as anemia, respiratory distress, renal failure, and cerebral malaria are observed in addition to cyclical fevers.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Parasitic infections (protists)
  Infections caused by Alveolates
   H00361  Malaria
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Parasitic diseases
   Malaria
    1F40  Malaria due to Plasmodium falciparum
     H00361  Malaria
    1F41  Malaria due to Plasmodium vivax
     H00361  Malaria
    1F42  Malaria due to Plasmodium malariae
     H00361  Malaria
    1F43  Malaria due to Plasmodium ovale
     H00361  Malaria
Pathway
hsa05144 Malaria   
Pathogen
Plasmodium falciparum [GN:pfa pfd pfh] (Falciparum malaria)
Plasmodium vivax [GN:pvx] (Vivax malaria)
Plasmodium knowlesi H [GN:pkn]
Plasmodium malariae
Plasmodium ovale
Drug
Doxycycline hyclate [DR:D02129]
Doxycycline calcium [DR:D03903]
Sulfadiazine [DR:D00587]
Chloroquine phosphate [DR:D02125]
Hydroxychloroquine sulfate [DR:D02114]
Primaquine phosphate [DR:D02126]
Tafenoquine succinate [DR:D10670]
Atovaquone and proguanil hydrochloride [DR:D02472]
Quinine sulfate [DR:D02262]
Mefloquine hydrochloride [DR:D00831]
Pyrimethamine [DR:D00488]
Artesunate [DR:D02482]
Artemether and lumefantrine [DR:D02484]
Comment
Vector: Anopheles gambiae (African malaria mosquito) [GN:aga]
Other DBs
ICD-11: 1F40 1F41 1F42 1F43
ICD-10: B50 B51 B52 B53
MeSH: D008288
MedlinePlus: 000621
Reference
  Authors
Antinori S, Galimberti L, Milazzo L, Corbellino M
  Title
Plasmodium knowlesi: the emerging zoonotic malaria parasite.
  Journal
Acta Trop 125:191-201 (2013)
DOI:10.1016/j.actatropica.2012.10.008
Reference
  Authors
Plewes K, Leopold SJ, Kingston HWF, Dondorp AM
  Title
Malaria: What's New in the Management of Malaria?
  Journal
Infect Dis Clin North Am 33:39-60 (2019)
DOI:10.1016/j.idc.2018.10.002
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