KEGG   DISEASE: Brazilian purpuric feverHelp
Entry
H01330                      Disease                                

Name
Brazilian purpuric fever
Description
Brazilian purpuric fever (BPF), which is caused by Haemophilus influenzae biogroup aegyptius (H. aegyptius), is a recently described pediatric disease that is often fatal. The vascular destruction is a distinctive trait, and little is known about the mechanism(s) of the overwhelming purpura fulminans that causes the high mortality. This disease is preceded by purulent conjunctivitis which resolves but is followed 10-14 days later by acute onset of fever associated with systemic toxicity, petechiae, purpura, and vascular collapse.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by other gamma proteobacteria
   H01330  Brazilian purpuric fever
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Other bacterial diseases
   1C18  Brazilian purpuric fever
    H01330  Brazilian purpuric fever
BRITE hierarchy
Pathogen
Haemophilus influenzae biogroup aegyptius [GN:hif]
Other DBs
ICD-11: 1C18
ICD-10: A48.4
MeSH: D006192
Reference
PMID:3262623
  Authors
Brenner DJ, Mayer LW, Carlone GM, Harrison LH, Bibb WF, Brandileone MC, Sottnek FO, Irino K, Reeves MW, Swenson JM, et al.
  Title
Biochemical, genetic, and epidemiologic characterization of Haemophilus influenzae biogroup aegyptius (Haemophilus aegyptius) strains associated with Brazilian purpuric fever.
  Journal
J Clin Microbiol 26:1524-34 (1988)
Reference
PMID:9727086
  Authors
Smoot LM, Bell EC, Paz RL, Corbin KA, Hall DD, Steenbergen JN, Harner AC, Actis LA.
  Title
Molecular and genetic analysis of iron uptake proteins in the brazilian purpuric fever clone of Haemophilus influenzae biogroup aegyptius.
  Journal
Front Biosci 3:D989-96 (1998)
Reference
  Authors
Musher DM
  Title
Haemophilus Species
  Journal
Medical Microbiology (1996)
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