Allergic contact dermatitis

Allergic contact dermatitis (ACD) is a T-cell mediated skin inflammation caused by repeated skin exposure to contact allergens. Although regarded as a dermatosis that is typically triggered by environmental factors, ACD may affect certain individuals more easily than others. A higher risk for polysensitization has been found for polymorphism in the TNFA (TNFA-308) and IL-16 (IL-16-295 C/C) genes.

Immune system disease

TNFA (polymorphism) [HSA:712] [KO:K03986]
IL-16 (polymorphism) [HSA:3603] [KO:K22628]

Nickel [CPD:C00291]
Fragrances
Cobalt [CPD:C00175]
Chrominium [CPD:C06268]
Peru balsam
Neomycin [CPD:C00384]
Rubber [CPD:C02321]

Triamcinolone acetonide [DR:D00983]
Dexamethasone [DR:D00292]
Dexamethasone sodium phosphate [DR:D00975]
Hydrocortisone [DR:D00088]
Hydrocortisone sodium succinate [DR:D00978]
Prednisolone [DR:D00472]
Prednisolone sodium phosphate [DR:D00981]
Prednisone [DR:D00473]
Methylprednisolone [DR:D00407]
Methylprednisolone sodium succinate [DR:D00751]
Methylprednisolone acetate [DR:D00979]
Cortisone acetate [DR:D00973]
Hydroxyzine hydrochloride [DR:D00672]
Hydroxyzine pamoate [DR:D01096]

PMID:19834255

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Individual susceptibility to occupational contact dermatitis.

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PMID:21166814

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PMID:12694213

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PMID:21489368

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PMID:19447733

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Allergic and irritant contact dermatitis.

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DOI:10.1684/ejd.2009.0686

PMID:11173201 (description, env_factor)

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DOI:10.1016/S0738-081X(00)00158-9

PMID:15243515 (env_factor)

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Contact dermatitis: a quarter century perspective.

J Am Acad Dermatol 51:S60-3 (2004)
DOI:10.1016/j.jaad.2003.01.002

PMID:24193097 (env_factor)

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Occupational and non-occupational allergic contact dermatitis: a follow-up study.

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DOI:10.1159/000354763

PMID:20672788 (drug)

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Diagnosis and management of contact dermatitis.

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(drug)

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The McGraw-Hill Companies, Inc. (2013)