KEGG   DISEASE: Allergic contact dermatitisHelp
Entry
H01357                      Disease                                

Name
Allergic contact dermatitis
Description
Allergic contact dermatitis (ACD) is a T-cell mediated skin inflammation caused by repeated skin exposure to contact allergens. Although regarded as a dermatosis that is typically triggered by environmental factors, ACD may affect certain individuals more easily than others. A higher risk for polysensitization has been found for polymorphism in the TNFA (TNFA-308) and IL-16 (IL-16-295 C/C) genes.
Category
Immune system disease
Brite
Human diseases [BR:br08402]
 Immune system diseases
  Allergies and autoimmune diseases
   H01357  Allergic contact dermatitis
 Skin diseases
  Skin and soft tissue diseases
   H01357  Allergic contact dermatitis
Human diseases in ICD-11 classification [BR:br08403]
 14 Diseases of the skin
  Skin disorders provoked by external factors
   Dermatitis due to exogenous factors
    EK00  Allergic contact dermatitis
     H01357  Allergic contact dermatitis
BRITE hierarchy
Gene
TNFA (polymorphism) [HSA:712] [KO:K03986]
IL-16 (polymorphism) [HSA:3603] [KO:K22628]
Env factor
Nickel [CPD:C00291]
Fragrances
Cobalt [CPD:C00175]
Chrominium [CPD:C06268]
Peru balsam
Neomycin [CPD:C00384]
Rubber [CPD:C02321]
Drug
Triamcinolone acetonide [DR:D00983]
Dexamethasone [DR:D00292]
Dexamethasone sodium phosphate [DR:D00975]
Hydrocortisone [DR:D00088]
Hydrocortisone sodium succinate [DR:D00978]
Prednisolone [DR:D00472]
Prednisolone sodium phosphate [DR:D00981]
Prednisone [DR:D00473]
Methylprednisolone [DR:D00407]
Methylprednisolone sodium succinate [DR:D00751]
Methylprednisolone acetate [DR:D00979]
Cortisone acetate [DR:D00973]
Other DBs
ICD-11: EK00
ICD-10: L23
MeSH: D017449
Reference
  Authors
Kezic S, Visser MJ, Verberk MM
  Title
Individual susceptibility to occupational contact dermatitis.
  Journal
Ind Health 47:469-78 (2009)
DOI:10.2486/indhealth.47.469
Reference
  Authors
Schnuch A, Westphal G, Mossner R, Uter W, Reich K
  Title
Genetic factors in contact allergy--review and future goals.
  Journal
Contact Dermatitis 64:2-23 (2011)
DOI:10.1111/j.1600-0536.2010.01800.x
Reference
  Authors
Westphal GA, Schnuch A, Moessner R, Konig IR, Kranke B, Hallier E, Ziegler A, Reich K
  Title
Cytokine gene polymorphisms in allergic contact dermatitis.
  Journal
Contact Dermatitis 48:93-8 (2003)
DOI:10.1034/j.1600-0536.2003.480208.x
Reference
  Authors
Toncic RJ, Lipozencic J, Martinac I, Greguric S
  Title
Immunology of allergic contact dermatitis.
  Journal
Acta Dermatovenerol Croat 19:51-68 (2011)
Reference
  Authors
Nosbaum A, Vocanson M, Rozieres A, Hennino A, Nicolas JF
  Title
Allergic and irritant contact dermatitis.
  Journal
Eur J Dermatol 19:325-32 (2009)
DOI:10.1684/ejd.2009.0686
Reference
PMID:11173201 (description, env_factor)
  Authors
Wolf R, Wolf D
  Title
Contact dermatitis.
  Journal
Clin Dermatol 18:661-6 (2000)
DOI:10.1016/S0738-081X(00)00158-9
Reference
PMID:15243515 (env_factor)
  Authors
Cohen DE
  Title
Contact dermatitis: a quarter century perspective.
  Journal
J Am Acad Dermatol 51:S60-3 (2004)
DOI:10.1016/j.jaad.2003.01.002
Reference
PMID:24193097 (env_factor)
  Authors
Macan J, Rimac D, Kezic S, Varnai VM
  Title
Occupational and non-occupational allergic contact dermatitis: a follow-up study.
  Journal
Dermatology 227:321-9 (2013)
DOI:10.1159/000354763
Reference
PMID:20672788 (drug)
  Authors
Usatine RP, Riojas M
  Title
Diagnosis and management of contact dermatitis.
  Journal
Am Fam Physician 82:249-55 (2010)
Reference
(drug)
  Authors
Papadakis MA, McPhee SJ, Rabow MW (ed).
  Title
Current Medical Diagnosis & Treatment 2013, Fifty-Second Edition
  Journal
The McGraw-Hill Companies, Inc. (2013)
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